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Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery
Gene Therapy (2007) 14, 682–689 This study describes a multifunctional envelope-type nano device (MEND) that mimics an envelope-type virus based on a novel packaging strategy. MEND particles contain a… more →
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Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery
tanlab wrote 7 months ago: Gene Therapy (2007) 14, 682–689 This study describes a multifunctional envelope-type nano device (ME … more →
Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins
tanlab wrote 7 months ago: Nature Biotechnology 27, 378 – 386 (2009) Although the classification of cell types often reli … more →
Asymmetric Shorter-duplex siRNA Structures Trigger Efficient Gene Silencing With Reduced Nonspecific Effects
tanlab wrote 7 months ago: Molecular Therapy (2009) 17 4, 725–732 Small interfering RNAs (siRNAs) are short, double-stranded RN … more →
A Bipedal DNA Brownian Motor with Coordinated Legs
tanlab wrote 7 months ago: Science, 2009, 324, 67 A substantial challenge in engineering molecular motors is designing mechanis … more →
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
tanlab wrote 7 months ago: Science, 2009, 324, 59 We report a strategy to create photodegradable poly(ethylene glycol)–based hy … more →
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
tanlab wrote 7 months ago: Science, 2009, 323, 1718 P-glycoprotein (P-gp) detoxifies cells by exporting hundreds of chemically … more →
A Role for RNAi in the Selective Correction of DNA Methylation Defects
tanlab wrote 7 months ago: Science, 2009, 323, 1600 DNA methylation is essential for silencing transposable elements and some g … more →
Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site
tanlab wrote 7 months ago: Science, 2009, 323, 1610 The interface between antibody and antigen is often depicted as a lock and … more →
Polyfluorophores on a DNA Backbone: A Multicolor Set of Labels Excited at One Wavelength
tanlab wrote 7 months ago: J. Am. Chem. Soc., 2009, 131, 3923 We recently described the assembly of fluorescent deoxyriboside m … more →
Green nanotechnology from tea: phytochemicals in tea as building blocks for production of biocompatible gold nanoparticles
tanlab wrote 7 months ago: J. Mater. Chem., 2009 Phytochemicals occluded in tea have been extensively used as dietary supplemen … more →
Continuous, Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic, Electrochemical Aptamer-Based Sensor
tanlab wrote 7 months ago: J. Am. Chem. Soc., 2009, 131, 4262 The development of a biosensor system capable of continuous, real … more →
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
tanlab wrote 7 months ago: Nature Chemical Biology, 2009, 5, 258 Stepwise differentiation from embryonic stem cells (ESCs) to f … more →
Affinity capture using chimeric membrane proteins bound to magnetic beads for rapid ligand screening by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
tanlab wrote 7 months ago: Rapid Communications in Mass Spectrometry, 2009, 23, 745 The rapid and specific detection of therape … more →
Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach
tanlab wrote 7 months ago: J. Am. Chem. Soc., 2009, 131, 378–386 The emerging field of global mass-based metabolomics provides … more →
Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX
tanlab wrote 7 months ago: Journal of Pathology, 2009 We report a new in situ tissue slide-based SELEX strategy targeting neopl … more →
Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis
tanlab wrote 8 months ago: PNAS, 2009, 106, 685 A biodegradable positron-emitting dendritic nanoprobe targeted at αvβ3 integrin … more →
Effects of linker sequences on vesicle fusion mediated by lipid-anchored DNA oligonucleotides
tanlab wrote 8 months ago: PNAS, 2009, 106, 979 Synthetic lipid–oligonucleotide conjugates inserted into lipid vesicles mediate … more →
Electron microscopy of whole cells in liquid with nanometer resolution
tanlab wrote 8 months ago: PNAS, 2009, 106, 2159 Single gold-tagged epidermal growth factor (EGF) molecules bound to cellular E … more →
Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure
tanlab wrote 8 months ago: PNAS, 2009, 106, 3125 Understanding molecular-scale architecture of cells requires determination of … more →
