In order to grow to a certain size solid tumors depend of innervation with oxygen and nutrients by blood vessels. The process of building new vessels from pre-existing ones, called angiogenesis, is crucial for this. 100 more words
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Bioimaging of Fluorescence-Labeled Mitochondria in Subcutaneously Grafted Murine Melanoma Cells by the “In Vivo Cryotechnique:” Nobohiko Ohno on the most important findings from this paper
Complete Figure Explanation: Mitochondrial volume varied among tumor cells and decreased in tumor cells expressing hypoxia markers. (A-D) Mitochondria-targeted DsRed2-positive cells (Mito, red in C) were scattered throughout tumor tissues and could be observed around blood vessels (arrowheads in C and D) and in necrotic tissue regions (arrows in C and D) immunostained with IgM (green in B and D). 489 more words
Now this is an old blood system! Paleontologists have identified the cardiovascular system of those little prehistoric critters: arthropods.