I love this, I wish I could frame it and put it on my wall!
If you were thinking about patting it with pineapple juice then SMH for shame! If not, then uhm... [caption id="" align="aligncenter" width="288"] (Unknown n.d.)[/caption] Okay hey so this is my last post on enzymes to wrap up EAW Now although EAW is coming to a close, Enzyme appreciation should never cease, ya feel me?! So anyway, I'm reblogging the post below, which I found by searching"enzyme", no 's', which is basically a home recipe for a natural facial exfoliation mask. Cool huh? Not really,not to me anyway. What I think is cool is the ingredient (papaya), well more so how it works! :D Let's jump right into it! [caption id="" align="alignnone" width="214"] (Unknown n.d.)[/caption] Papain, a latex enzyme found in papaya (,Konno and Hirayama et al. 2004, 370-378) is an endopeptidase, amidase, and esterase (Worthington-biochem.com 2014). Yep, just your non-average, extra-ordinary (ik it's one word, that was just for extra effect) jack-of-all-trades.
Papain's got quite a few uses, which you can Google if you so desire :) We gotta focus, let's understand what I just typed, together! An endopeptidase is "an enzyme that catalyses (duh) the cleavage of peptide bonds within a polypeptide or protein. Peptidase refers to the fact that it acts on peptide bonds (makes sense) and endopeptidase refers to the fact that these are internal bonds.An exopeptidase catalyses the cleavage of the terminal peptide bond, releasing a single amino acid or dipeptide from the peptide chain."(Medterms 2012) An amidase is "1. Any group of enzymes that catalyse the cleavage of carbon-nitrogen bonds of amides. 2. An enzyme that catalyses the cleavage of thencwrbon-nitrogen bond of a monocarboxlylic acid amide to form a momocarboxylic amide and amonia." (Saunders 2007) An esterase is "any enzyme which catalyses the hydrolysis of an ester into its alcohol and acid." (Saunders 2007) Ha ha ha...what does any of that even mean?? Wellll, I think what it all boils down to are amino acids! Ba dum tss!... get it? Boils down a protein to....*clears throat* ahem, anyway, anyway, I think basically it means that papain 1) cuts up proteins and polypeptide chain, I.e, into pieces; therefore you end up with shorter polypeptide chains or broken proteins (which comprises of many polypeptide chains); you don't end up with amino acids because that's what exopeptidases do :)
2) messes up amides OR trims an amide to make a smaller amide + ammonia 3) turns esters back into alcohols and acids. I bet now you can think of a few uses for papain without Google *smirks* So papain and exfloiation, what's the connection? It would help you to know what exfoliaton means. [caption id="attachment_505" align="aligncenter" width="175"] (Oxforddictionaries.com n.d)[/caption] Now, are you seeing the connection more clearly? No? Okay look at this real quick before I tell you, cause when I do you'll be like, "chupz, oh shucks! Yeah boy, that makes sense! Smh, I knew it you know, it was coming to me..." or something like that. Now you see how it works? Keratin, collagen, and elastin? What are those? Proteins, that's right! How you feeling now? Lol, doh beat up, you will get it next time! So because papain is an endonuclease, the idea is that it would breakdown the dead skin cells, and when you wash you face with warm (nudge nudge, hint hint) water, it would wash them away. It's pretty simple, I know I could've just told you, but that's not how learning works, I had to walk you through it and answer your why's before you asked :) BTW, you know that esters are fats and oils right? Okay cool, so next point..
Problems, problems, problems, smh.
These problems!1) if you're allergic to latex the you're probably going to be allergic to papain :( and if you don't know why then you weren't paying attention cause I totally said it, first line -_- 2) if you use oils or oil based products on your face and some (along with papain) gets into your eyes or mouth then you know what will happen? (Rhetorical question, you do know, I just went over this, think it through) 3) bad things can happen, yeah like being poisoned, if you ingest too much papain in one sitting..well that of course depends on your diet. Why though? Think it through, you know this one too, there will be no spoon-feeding done here. Think esters, think food :) You can't have the good without the bad, you know what I'm saying? So now you know, let's exfoliate bro! Oh wow, this post was longer than expected, lol sorry bout that! --Zee
HowStuffWorks. "HowStuffWorks "What is skin made of?"." n.d.. http://health.howstuffworks.com/skin-care/information/anatomy/what-is-skin-made-of.htm (accessed 7 Mar 2014).
Konno, Kl, C Hirayama, M Nakamura, K Tateishi, Y Tamura, M Hattori and K Kohno. "Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex.." Plant J, Feb, 2004.
Medterms. "Endopeptidase." 2012. http://www.medterms.com/script/main/art.asp?articlekey=39552 (accessed 7 Mar 2014).
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