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Blogs about: Egfr

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Friday Science Review: August 28, 2009

RChan wrote 3 months ago: A Montreal flavour this week… Critical link between EGFR and Src oncogenes: On the heels of la … more →

Tags: Friday Science Review, Richard Chan, Cancer, IRCM, Jnk, Leukemia, McGill, met, Natural Killer cells

Halting DNA repair in cancer cells

smnewsletters wrote 5 months ago: A randomized trial announced the recent annual meeting of the American Society of Clinical Oncology … more →

Tags: Cancer, breast cancer, breast, Multiple Myeloma, triple negative breast cancer, DNA repair, febrile neutropenia, Hodgkin's Lymphoma

Cell-surface glycosylation enables brain metastasis

annalsofneurology wrote 5 months ago:   Brain metastases in breast cancer patients tend to be a late event compared to other organs, sugge … more →

Tags: Discoveries in Neuroscience, Blood Brain Barrier, brain metastases, breast cancer, estrogen-receptor, cyclooxigenase COX2, epidermal growth factor receptor, HBEGF, A2

Your eGFR might be a little inaccurate

PKDnotes wrote 6 months ago: Everyone with PKD gets their GFR (Glomerular Filtration Rate, estimated or otherwise calculated) tes … more →

Tags: Research and support, Kidney Disease, Kidney Function, Lab Tests, Pathology, pkd, Polycystic kidney disease

How to Predict the Probability of ESRD

underwritingsolutionsllc wrote 7 months ago: Medical News: Two Tests Are Better Than One for Renal Disease Prognosis – in Nephrology, ESRD … more →

Tags: Medical News, Underwriting, Lifelong Learning, ESRD

Atrial fibrillation? Check for proteinuria

smnewsletters wrote 8 months ago: In people with atrial fibrillation, proteinuria increases the risk of stroke independent of other ri … more →

Tags: Family Medicine, Internal Medicine, Cardiovascular, Geriatrics, Stroke, warfarin, Stroke, thrombosis, atrial fibrillation

European Researchers Find Estrogen Receptor Gene Amplification Occurs Rarely in Ovarian Cancer2 comments

Paul Cacciatore wrote 9 months ago: “… ESR1 [gene] amplification is an uncommon mechanism for estrogen receptor overexpressi … more →

Tags: Medical Study Results, Anti-Estrogen Therapy, ovarian cancer, letrozole, Femara, tamoxifen, aromatase inhibitors, estrogen receptor positive, estrogen gene amplification

Erbitux (Cetuximab) in First-Line Treatment Colorectal Cancer Mangement1 comment

bmirtsching wrote 1 year ago: CORT has conducted research and treatment studies with the monoclonal anti-EGFR (anti-epidermal grow … more →

Tags: colorectal cancer, bevacizumab, Avastin, cetuximab, Erbitux, Oxaliplatin, Irinotecan, Colon Cancer, Metastatic Colon Cancer

Millennium present data on kinase programs at EORTC-NCI-AACR meeting

crimsoncanary wrote 1 year ago: Data presented at the EORTC NCI AACR meeting detail data and progress on Millennium kinase programs: … more →

Tags: Aurora, Aurora A, her, HER2, Millennium, MLN-8237, MLN8237, pdgf, TAK-285

Boehringer Ingelheim provide update on kinase programs

crimsoncanary wrote 1 year ago: Boehringer have provided a pipeline update including information on kinase inhibitors, and announces … more →

Tags: ErbB2, HER2, BIBF1120, BIBF-1120, phase iii, ErbB1, VEGFR, FGFR, Plk1

GSK respond to negative NICE recommendation on Tykerb

crimsoncanary wrote 1 year ago: GSK have responded to the NICE recommendationi that Tyverb (lapatinib) should not be used in the NHS … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, HER2, Tykerb, GSK572016, GSK-572016, GSK

Abbott publish series of EGFR/ ErbB-2 inhibitor

crimsoncanary wrote 1 year ago: Abbott have published a series of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidine EGFR/ ErbB-2 Inhib … more →

Tags: kinase, ErbB-2, Research, Preclinical, Abbott

GSKs Tykerb (lapatinib) effective in advanced head and neck cancer

crimsoncanary wrote 1 year ago: Phase II data presented at the European of Medical Oncology (ESMO) show that GSK’s Tykerb (lap … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, HER2, Tykerb, GSK572016, GSK-572016, GSK

Phase II nimotuzumab data supports continued development

crimsoncanary wrote 1 year ago: YM Biosciences have released Phase II data that show its EFGR antibody nimotuzumab to be effective i … more →

Tags: Kinase receptor, phase ii, EGF, YM BioSciences, nimotuzumab, DE-766, DE766, Theraloc, Daiichi Sankyo

YM Biosciences EGFR MAb nimotuzumab safe in Phase I

crimsoncanary wrote 1 year ago: Data to be presented at the AACR Centennial Conference on Translational Cancer Medicine today will d … more →

Tags: Kinase receptor, Phase I, EGF, YM BioSciences, nimotuzumab, DE-766, DE766, Theraloc, Daiichi Sankyo

Hana Biosciences Menadione found to restore kinase without inhibiting the Anti-Tumor Effect of Erlotinib

crimsoncanary wrote 1 year ago: Preclinical data presented at the European Society for Medical Oncology Conference show Hana Bioscie … more →

Tags: kinase, Research, Preclinical, menadione, Hana Biosciences

Coadministration of AZD0530 and Gefitinib increases growth inhibition in vitro

crimsoncanary wrote 1 year ago: In vitro studies with Src inhibitor AZD0530 and EGFR kinase inhibitor Geftinib show that treatment w … more →

Tags: kinase, AstraZeneca, EGF kinase, Iressa, gefitinib, Research, src, Preclinical, AZD0530

Takeda submit Japanese NDA for panitumumab in progressed and/or relapse colorectal cancer

crimsoncanary wrote 1 year ago: Takeda have submitted a New Drug Application to the Ministry of Health Labour and Welfare in Japan f … more →

Tags: Kinase receptor, Regulatory, Vectibix, panitumumab, Amgen, monoclonal, Takeda, ABX-EG

Preemptive Treatment May Significantly Reduce Skin Toxicities in Patients Receiving Panitumumab

crimsoncanary wrote 1 year ago: Data presented today at the 10th World Congress on Gastrointestinal Cancer shows that preemptive tre … more →

Tags: Kinase receptor, Vectibix, panitumumab, ABX-EGF, Amgen, monoclonal, Takeda


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