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Enhanced Transcriptome Maps from Multiple Mouse Tissues Reveal Evolutionary Constraint in Gene Expression for Thousands of Genes

Enhanced Transcriptome Maps from Multiple Mouse Tissues Reveal Evolutionary Constraint in Gene Expression for Thousands of Genes
Dmitri Pervouchine, Sarah Djebali, Alessandra Breschi, Carrie A Davis, Pablo Prieto Barja, Alex Dobin, Andrea Tanzer, Julien Lagarde, Chris Zaleski, Lei-Hoon See, Meagan Fastuca, Jorg Drenkow, Huaien Wang, Giovanni Bussotti, Baikang Pei, Suganthi Balasubramanian, Jean Monlong, Arif Harmanci, Mark Gerstein, Michael A Beer, Cedric Notredame, Roderic Guigo, Thomas R Gingeras… 163 more words

Gene Expression

Sharing and specificity of co-expression networks across 35 human tissues

Sharing and specificity of co-expression networks across 35 human tissues
Emma Pierson, GTEx Consortium, Daphne Koller, Alexis Battle, Sara Mostafavi
doi: http://dx.doi.org/10.1101/010843

To understand the regulation of tissue-specific gene expression, the GTEx Consortium generated RNA-seq expression data for more than thirty distinct human tissues. 187 more words

Gene Expression

Internet tools for studying gene expression

  1. Genevestigator for plants (can also be used for biomedicine/pharma). The site requires login, and only the most basic features are available for free.
  2. The Arabidopsis eFP browser…
  3. 33 more words
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Biochemical constraints on genes involved in early embryonic development.

Chemical reactions form the foundation of life, yet such elementary activities are rarely considered when trying to understand higher-level processes, such as embryonic development. Nevertheless, as recently shown by… 747 more words

These Are the Cells You’re Looking for: Scientists Devise New Way to Extract Bone-Making Stem Cells from Fat

Buried within our fat tissue are stashes of stem cells—a hidden reservoir of cells that, if given the right cues, can transform into cells that make up bone, cartilage or fat. 535 more words

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