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Blogs about: Gsk572016

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GSK respond to negative NICE recommendation on Tykerb

crimsoncanary wrote 1 year ago: GSK have responded to the NICE recommendationi that Tyverb (lapatinib) should not be used in the NHS … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

GSKs Tykerb (lapatinib) effective in advanced head and neck cancer

crimsoncanary wrote 1 year ago: Phase II data presented at the European of Medical Oncology (ESMO) show that GSK’s Tykerb (lap … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Tykerb receives conditional EU marketing approval for HER2 breast cancer

crimsoncanary wrote 1 year ago: GlaxoSmithKline have received a conditional marketing authorisation from the european autorities for … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Phase II data on lapatinib (Tykerb) presented at ASCO

crimsoncanary wrote 1 year ago: Data presented at ASCO highlight recent findings with lapatinib including: - Phase II data on Lapati … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Phase I dose escalation trial of Lapatinib in combination with trastuzumab

crimsoncanary wrote 1 year ago: Phase I results show that combining 1000 mg lapatinib and weekly trastuzumab is well tolerated … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Tykerb plus Herceptin increase PFS

crimsoncanary wrote 1 year ago: Results from a Phase III trial show that the administration of Tykerb in combination with Herceptin … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Lapatinib enters global early breast cancer trial

crimsoncanary wrote 1 year ago: GSK and the Breast International Group (BIG) are initiating a phase III clinical trial of Lapatinib … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Lapatinib demonstrates efficacy in renal cancer

crimsoncanary wrote 1 year ago: In a phase III study in renal cell carcinoma patients lapatinib displayed equivalent efficacy to hor … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Lapatinib safe and efficacious as First-Line Therapy for ErbB2-Amplified Locally Advanced or Metastatic Breast Cancer

crimsoncanary wrote 1 year ago: Lapatinib has demonstrated efficacy and was well tolerated as first-line therapy in ErbB2-amplified … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

EMEA issues revised positive opinion on lapatinib in breast cancer

crimsoncanary wrote 1 year ago: The EMEA’s CHMP division has issued a revised positive opinion for lapatinib in breast cancer. … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK

Lapatinib decreases tumorigenic breast cancer stem cells

crimsoncanary wrote 1 year ago: Data presented at the 6th European Breast Cancer Conference shows tumorigenic breast cancer cells ar … more →

Tags: kinase, lapatinib, ErbB-2, ErbB2, EGFR, HER2, Tykerb, GSK-572016, GSK


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