SMFH people are killing me with this damn Obama drama, I mean really have they forgetten how much Bush fucked up the whole world over these last eight years, and yes I said the whole world not America the WHOLE FUCKEN WORLD. Once again we got another dumb ass not living in reality and acting as if as soon as Obama came into office shit was going to be better, I swear people make me sick. Heres what NY Post’s columnist Michael Goodwin who also voted for Obama like myself btw, has to say:

“President Obama, for whom I voted because I believed he was the best choice available, is a profound disappointment. I now regard his campaign as a sly bait-and-switch operation, promising one thing and delivering another. Shame on me.

Equally surprising, he has become an insufferable bore. The grace notes and charm have vanished, with peevishness and petty spite his default emotions. His rhetorical gifts now serve his loathsome habit of fear-mongering.

“Time is running out,” he says, over and again. He said it on health care, on the stimulus, in Copenhagen, on Iran.

Instead of provoking thought and inspiring ideas, the man hailed for his Ivy League nuance insists we stop thinking and do what he says. Now.

His assertion we will go bankrupt unless Congress immediately adopts the health monstrosity marks a new low. At least it did until he barged into a meeting in Copenhagen to insult the Chinese with the same do-it-now arrogance on carbon emissions. Read More…“

Why wont people just admit it, the ones that are hella mad and  are saying Obama isnt doing everything that they want as if he has a magic button and can just push it and make everything better, just voted for him because they wanted a damn Black President YA I FUCKEN SAID IT you dumb dumbs just wanted a damn Black President and thought all would be well. Well guess WHAT reality check BUSH fucked up the whole world and some therefore its going to take some fucken time to get this shit back on track. Fucken breath or move your ass to Canada. UUHHKKK!

ScienceDaily (Dec. 19, 2009) — Carotenoids, found in green leafy vegetables and colored fruits, have been found to increase visual performance and may prevent age-related eye diseases, according to a study in the Journal of Food Science, published by the Institute of Food Technologists.

,
Authors from the University of Georgia compiled the results of multiple studies on the effects of the carotenoids lutein and zeaxanthin on visual performance. These carotenoids play an important role in human vision, including a positive impact on the retina.
After reviewing the various studies, the authors concluded that macular pigments, such as lutein and zeaxanthin do have an effect on visual performance. Lutein and zeaxanthin can reduce disability and discomfort from glare, enhance contrast, and reduce photostress recovery times. They can also reduce glare from light absorption and increase the visual range.
Lead author Dr. Billy R. Hammond Jr. noted that the research of the effects of lutein and zeazanthin are important because “it is clear that they could potentially improve vision through biological means. For example, a study conducted in 2008 suggests that the pigments protect the retina and lens and perhaps even help prevent age-related eye diseases such as macular degeneration and cataract.”
http://www.sciencedaily.com/releases/2009/12/091218125804.htm

What is self evident has taken years to find out.
ScienceDaily (Dec. 19, 2009) — Why does a human baby need a full year before it can start walking, while a newborn foal gets up on its legs almost directly after birth? Scientist have assumed that human motor development is unique because our brain is unusually complex and because it is particularly challenging to walk on two legs. But now a research group at Lund University in Sweden has shown that human babies in fact start walking at the same stage in brain development as most other walking mammals, from small rodents to elephants.

The findings are published in the journal PNAS.
The Lund group consists of neurophysiologists Martin Garwicz and Maria Christensson and developmental psychologist Elia Psouni. Contrary to convention, they used conception and not birth as the starting point of motor development in their comparison between different mammals. This revealed astonishing similarities among species that diverged in evolution as much as 100 million years ago. — Humans certainly have more brain cells and bigger brains than most other terrestrial mammalian species, but with respect to walking, brain development appears to be similar for us and other mammals. Our study demonstrates that the difference is quantitative, not qualitative, says Martin Garwicz.
Based on knowledge about development in other mammals it is therefore possible to actually predict with high precision when human babies will start to walk. This is a very unexpected and provocative finding.
The notion that humans have a unique position among mammals is not only deeply rooted among lay people, but is also reflected in fundamental assumptions in different research fields related to human development and human brain evolution.
“Our study strongly contradicts this assumption and thereby sheds new light on theories in, for instance, evolutionary and developmental biology,” says Martin Garwicz. “On the other hand, our findings fit well with the substantial similarities between the genomes of different mammals. Perhaps these similarities are after all not that surprising — although the end products ‘human’ and ‘rat’ may be very different, our study suggests that the building blocks and principles for how these building blocks interact with one another during development could be the same.”
The study originated in an attempt by the group to translate behavioral milestones of motor development between two distantly related species. The similarities in relative developmental time courses between the two species were so striking that the scientists started to wonder whether the regularity applied to other mammals and ultimately also to humans.
The Lund group has now compared 24 species, which together represent the majority of existing walking mammals. Some, like the great apes, are closely related to us evolutionarily while others, such as rodents, hoofed animals, and elephants, diverged from our evolutionary path about 90-100 million years ago.
Despite this, and regardless of differences in various species’ brain and body size, gestation time, and brain maturity at birth, the comparison shows that the young from all species start walking at the same relative time point in brain development. Humans may be unique, but not in this particular way. When the nervous system has reached a given level of maturity, you learn to walk, whether you are a hedgehog, a foal, or a human baby…
http://www.sciencedaily.com/releases/2009/12/091215160851.htm

ScienceDaily (Dec. 15, 2009) — Researchers at Rice University and Baylor College of Medicine (BCM) have created a single nanoparticle that can be tracked in real time with MRI as it homes in on cancer cells, tags them with a fluorescent dye and kills them with heat. The all-in-one particle is one of the first examples from a growing field called “theranostics” that develops technologies physicians can use to diagnose and treat diseases in a single procedure.

The research is available online in the journal Advanced Functional Materials. Tests so far involve laboratory cell cultures, but the researchers said MRI tracking will be particularly advantageous as they move toward tests in animals and people.
“Some of the most essential questions in nanomedicine today are about biodistribution — where particles go inside the body and how they get there,” said study co-author Naomi Halas. “Noninvasive tests for biodistribution will be enormously useful on the path to FDA approval, and this technique — adding MRI functionality to the particle you’re testing and using for therapy — is a very promising way of doing this.”
Halas, Rice’s Stanley C. Moore Professor in Electrical and Computer Engineering and professor of chemistry and biomedical engineering, is a pioneer in nanomedicine. The all-in-one particles are based on nanoshells — particles she invented in the 1990s that are currently in human clinical trials for cancer treatment. Nanoshells harvest laser light that would normally pass harmlessly through the body and convert it into tumor-killing heat.
In designing the new particle, Halas partnered with Amit Joshi, assistant professor in BCM’s Division of Molecular Imaging, to modify nanoshells by adding a fluorescent dye that glows when struck by near-infrared (NIR) light. NIR light is invisible and harmless, so NIR imaging could provide doctors with a means of diagnosing diseases without surgery.
In studying ways to attach the dye, Halas’ graduate student, Rizia Bardhan, found that dye molecules emitted 40-50 times more light if a tiny gap was left between them and the surface of the nanoshell. The gap was just a few nanometers wide, but rather than waste the space, Bardhan inserted a layer of iron oxide that would be detectable with MRI. The researchers also attached an antibody that lets the particles bind to the surface of breast and ovarian cancer cells.
In the lab, the team tracked the fluorescent particles and confirmed that they targeted cancer cells and destroyed them with heat. Joshi said the next step will be to destroy whole tumors in live animals. He estimates that testing in humans is at least two years away, but the ultimate goal is a system where a patient gets a shot containing nanoparticles with antibodies that are tailored for the patient’s cancer. Using NIR imaging, MRI or a combination of the two, doctors would observe the particles’ progress through the body, identify areas where tumors exist and then kill them with heat.
“This particle provides four options — two for imaging and two for therapy,” Joshi said. “We envision this as a platform technology that will present practitioners with a choice of options for directed treatment.”
Eventually, Joshi said, he hopes to develop specific versions of the particles that can attack cancer at different stages, particularly early stage cancer, which is difficult to diagnose and treat with current technology. The researchers also expect to use different antibody labels to target specific forms of the disease. Halas said the team has been careful to choose components that are either already approved for medical use or are already in clinical trials.
“What’s nice is that every single component of this has been approved or is on a path toward FDA approval,” Halas said. “We’re putting together components that all have good, proven track records.”
Bardhan and BCM postdoctoral researcher Wenxue Chen are co-primary authors of the paper. Additional Rice co-authors include Emilia Morosan, assistant professor of physics and astronomy, and graduate students Ryan Huschka and Liang Zhao. Additional BCM co-authors include Robia Pautler, assistant professor of neuroscience and radiology, postdoctoral researcher Marc Bartels and graduate student Carlos Perez-Torres.
The research was sponsored by the Air Force Office of Scientific Research, the Welch Foundation and the Department of Defense’s Multidisciplinary University Research Initiative.

ScienceDaily (Dec. 11, 2009) — Approximately 20 percent of dialysis patients undergoing a percutaneous coronary intervention (PCI; procedure such as angioplasty) are given an antithrombotic medication they should not receive, which may increase their risk for in-hospital bleeding, according to a study in the December 9 issue of JAMA.
See Also:

“In the United States, medication errors are implicated in more than 100,000 deaths annually. Medication errors include adverse drug reactions related to inappropriately prescribed or administered drugs. To minimize inappropriate medication use, the U.S. Food and Drug Administration (FDA) guides pharmaceutical manufacturers and clinicians through drug labeling of which medications are contraindicated or not recommended for use in specific patient groups,” the authors write. “Little is known about the use of such medications and their effects on outcomes in clinical practice.”
Thomas T. Tsai, M.D., M.Sc., of the Denver VA Medical Center and University of Colorado Denver, and colleagues examined the use of the contraindicated/not-recommended antithrombotic agents enoxaparin and eptifibatide among dialysis patients undergoing percutaneous coronary intervention (PCI) and their association with outcomes. The researchers used data from the National Cardiovascular Data Registry (NCDR) from 829 U.S. hospitals on 22,778 dialysis patients who underwent PCI between Jan. 2004 and August 2008. The study focused on the outcomes of in-hospital bleeding and death.
The researchers found that overall, 5,084 patients (22.3 percent) received a contraindicated antithrombotic medication; 2,375 (46.7 percent) received enoxaparin, 3,261 (64.1 percent) received eptifibatide, and 552 (10.9 percent) received both. In unadjusted analysis, patients who received contraindicated antithrombotics experienced higher rates of in-hospital major bleeding (5.6 percent vs. 2.9 percent) and death (6.5 percent vs. 3.9 percent). Further analysis indicated that receipt of contraindicated antithrombotics was significantly associated with increased in-hospital major bleeding, but no significant association was found with in-hospital death.
“This study therefore demonstrates that these medications are used in clinical practice despite FDA-directed labeling, and their use is associated with adverse patient outcomes,” the authors write.
“Educational efforts targeting clinicians who prescribe these medications and quality improvement interventions, such as amending clinical pathway order sets to include consideration of renal function, are urgently needed.”

Incredibly, almost 50% of all local business still do not own a website - a statistic which is virtually unchanged for more than 5 years. 

Despite all the compelling reasons to get online, many local businesses still risk their online representation to unchecked review sites, third-party aggregators and inaccurate databases. I speak with local business owners every day, and although their reasons are understandable (“no time”,  “don’t know where to start”, “I have a guy doing it”) this gamble costs them any hope of reaching new customers and generating additional leads. 

I think my most recent experience is typical  - this week I finally decided to see a Chiropractor – 18 months of neck pain is enough. Like many, I started by asking friends and sent out an email seeking advice. I received three solid recommendations, and then went online to check ratings, reputation, location, phone numbers and overall credibility. I searched for their ”names” + “city” and expected to find all three quickly. I didn’t, and this story is exactly what the research confirms; a Nielsen/NetRatings survey found that 85% of people agreed that a website is an important factor in earning a consumer’s trust.   

The first Chiropractor only came up through various third-party sites like Merchant Circle - limited information and no link to a website. The second candidate was partially visible (bottom of first page) via an Internet Yellow Pages, good listing information but again – no link to a website. Neither of these two firms were even in Google Maps! The third was at the top of the results page with their own website – here.

The site is nothing extraordinary – and there are certainly some elements which could be improved (the link to the site’s developer is even broken),  but the point is this: I felt more comfortable in literally ”risking my neck” with this local business. They appear to be more credible, up-to-date and qualified. They are also smart enough to realize that a businesses online representation is too important to leave up to other uncontrollable sources. Even the most basic of websites can properly position you reach new customers. 

What’s next? Making the site visible! After all, what good is this marketing tool if it cannot be found? Here are some tips for Chiropractors, and all businesses should consider the various optimization and pay-per-click options available.

On Saturday I attended a free public lecture on obesity in Sydney.

The lecture featured professors of pharmacology, nutrition and medicine from Australia’s top universities.

The standout speaker was undoubtedly Professor of Medicine, Dr. Joseph Proietto of the University of Melbourne. Dr. Proietto showed palpable frustration with those who blame the obese for their condition and flatly rejected the notion that obesity is self-inflicted.

Here’s what I learned from the lecture.

KEY MESSAGES

Obesity is epigenetic. There are hundreds of genes related to obesity, and any number of gene variations can make a person more inclined to gain weight. Two people with the same diet and exercise patterns will have vastly different body shapes and weights, if they inherited different gene variations.

Weight is Regulated. Your body and in particular, your brain, keep your weight under tight control. Your body has an exquisitely complicated system for managing hunger, satiety, and weight gain and loss.

Weight is Defended. Your body will fight tooth and nail to defend the weight it has. The obese who lose most of their excess weight only to regain it within a short time are a classic example of how the body defends its original weight.

Environment is Facilitative, Not Causative. Obesity is not caused by excessive eating and laziness. It’s caused by genes that predispose people to gain weight, interacting with an environment in which a person eats more than required and exercises less than needed, to maintain a healthy weight. The eating and exercise patterns of an obese person may be identical to or better than those of a genetically skinny person, but they will gain weight nonetheless, and the skinny person will never see the effects. This is because the primary cause of obesity is genes, genes, genes.

OTHER FACTS AND FIGURES

Who’s Overweight or Obese?  2/3 of Australian men, 1/2 of Australian women, and 1/4 of Australian children and adolescents are overweight or obese. In America, rates of obesity are higher for each population group.

Who’s Gaining the Most Weight?  In this order: 25-34 year olds; 35-44 year olds; 45-54 year olds. So it’s not the middle-aged, it’s the twenty-somethings. And women are gaining more weight than men.

Is the Problem New?  Yes. Rates of overweight and obesity have skyrocketed in only one generation. For example, in 1985, 1 in 10 Australian children were overweight or obese. In 2004, 1 in 4.

Why are We Gaining Weight Now?  Given that our genetic make-up has not changed, subtle changes in our eating, activity and environment are responsible for the rapid increase in obesity in just a generation. However, these changes have affected people differently depending upon their genetic make-up and predisposition for gaining weight.

How Has Our Eating Changed?  Portions have slowly increased to massive sizes since the 1980’s. In terms of specific foods, the biggest culprits have been sodas, chips and other snack foods – all completely unnecessary for nutrition.

Side note: Nutrition labels on the backs of food boxes are based on the recommended daily allowances for a 70 kg (154 lb) male. If you’re not a 154 lb man, that nutrition label does not apply to you.

How Have Our Activity Levels Changed?  There’s been a drastic drop in the rates and quantity of incidental physical activity, like walking and cycling for transport. Incidental activity, unlike purposeful exercise, is performed for practical purposes other than fitness. As levels of incidental exercise have decreased, levels of small screen recreation have increased. Small screen recreation includes television, video games and computer activity.

Increased time sitting: the number of minutes or hours sitting is a major risk factor for overweight and obesity, independent of the number of minutes exercising or moving. This suggests moving, always moving, is a valid way of reducing one’s risk, and that sitting for 12 hours a day then doing one hour of aerobics is not necessarily superior.

How Has Our Environment Changed?  This was not discussed much, but see my other post The overweight scapegoat for a discussion on exactly this.

Does it Matter Where You Carry Weight?  Yes. The greatest health risk involves abdominal or central obesity. Thus, the apple-shaped person who carries his weight in his stomach is at considerably greater risk of chronic disease than the pear-shaped person with large hips, thighs and buttocks.

Who is At Greater Risk of Becoming Obese?  People with a genetic predisposition to gain weight, if they’re exposed to a particular environment and adopt a pattern of eating and activity that promotes weight gain. Other groups include:

People who were born weighing ≤ 2.5 kg (5.5 lbs)

People whose mothers are overweight or obese

People whose mothers were overweight or obese during pregnancy

Women at menopause – they engage in less purposeless movement (fidgeting) and begin to shift excess weight from their lower body to their stomachs. The average women will see a 4 cm (1.5 in) increase in waist size during menopause.

How Do You Lose Weight? Rapid drops in weight from extreme exercise and diet activity are not sustainable. A healthful diet and regular exercise in the longterm can produce weight loss over time, but this is extremely difficult, particularly for the obese. While everyone has anecdotal evidence of successful weight loss through diet and exercise, medical studies have shown diet and exercise are largely ineffective in producing significant weight loss in the long-term. This makes obesity prevention critical.

However, some people are successful in losing weight and keeping it off. The National Weight Control Registry is a registry of people in America who have successfully lost weight in the long-term. So far the study has shown that among those who have successfully lost weight:

• 78% eat breakfast every day
• 75% weigh themselves at least once a week
• 62% watch less than 10 hours of TV per week
• 90% exercise on average 1 hour per day

Do Obesity Drugs Work?  Dr. Proietto believes the development of effective obesity drugs is “absolutely essential” to combatting the body’s overwhelming neuroendocrine response in opposition to weight loss. Drugs would be most useful in helping patients maintain weight loss, not achieve it.

FINAL THOUGHTS

Some skinny people with bad eating and exercise habits suck. They think they have better habits than obese people. They think they eat healthier and exercise more. They think they have more self-discipline and impulse control. They think they’re just plain better than obese people.

They don’t know anything.

http://healthit.hhs.gov/blog/onc/

“Dr. David Blumenthal, HHS’ National Coordinator for Health Information Technology, today announced the launch of Health IT Buzz, a new blog that will allow readers to learn more about health information technology (health IT) and provide a space for consumers, providers, policymakers, and technology experts to share their ideas and concerns regarding health IT.”–From News Release.

Depression and anxiety can be tackled only by the individual concerned.Medicines and counseling can go only thus far.What is needed is understanding of some facts.
Out of desire comes attachment,from attachment expectations,expectations lead to lead to frustration,it leads to depression.
We have had many desires during our life time.If we sit down and ponder what was interesting and pleasurable at one point of time , no longer excites us, at times repugnant right now..The things we desired for retain their nature then and now.Then why we do not get the same pleasure out of it?Reason is that pleasure does not lie in things per se.They are our attitudes towards them. When the attitude changes, the whole picture changes.Therefore accept things in life as they are and not attach value to it.Do not carry it forward for our attitude may change and we may even be unhappy about the the things we liked.This is the truth.
Anxiety arises when we feel what we have done or achieved is not enough or things do not happen the way we want them to happen.If we are sure we have done our best, that is it.We can do no more.Accept your limitations.Do not set your goals too high.Remember,whatever you achieve is naught when you depart.
Things happen, controlled by various factors ,us being only a factor and not THE factor.As said earlier do your best and leave it at that.
Another reason for depression and anxiety is comparisons .No two things in the world are identical ;at best they are similar.Never try to be other than what you are.You too have a function and a purpose in the scheme of the Universe.
These are few tips to beat anxiety and depression

ScienceDaily (Nov. 18, 2009) — A study by researchers at the University of Bergen, Norway, and the Institute of Psychiatry (IoP) at King’s College London has found that depression is as much of a risk factor for mortality as smoking.

Utilising a unique link between a survey of over 60,000 people and a comprehensive mortality database, the researchers found that over the four years following the survey, the mortality risk was increased to a similar extent in people who were depressed as in people who were smokers.
Dr Robert Stewart, who led the research team at the IoP, explains the possible reasons that may underlie these surprising findings: ‘Unlike smoking, we don’t know how causal the association with depression is but it does suggest that more attention should be paid to this link because the association persisted after adjusting for many other factors.’
The study also shows that patients with depression face an overall increased risk of mortality, while a combination of depression and anxiety in patients lowers mortality compared with depression alone. Dr Stewart explains: ‘One of the main messages from this research is that ‘a little anxiety may be good for you’.
‘It appears that we’re talking about two risk groups here. People with very high levels of anxiety symptoms may be naturally more vulnerable due to stress, for example through the effects stress has on cardiovascular outcomes. On the other hand, people who score very low on anxiety measures, i.e. those who deny any symptoms at all, may be people who also tend not to seek help for physical conditions, or they may be people who tend to take risks. This would explain the higher mortality.’
In terms of the relationship between mortality and anxiety with depression as a risk factor, the research suggests that help-seeking behaviour may explain the pattern of outcomes. People with depression may not seek help or may fail to receive help when they do seek it, whereas the opposite may be true for people with anxiety.
Dr Stewart comments: ‘It would certainly not surprise me at all to find that doctors are less likely to investigate physical symptoms in people with depression because they think that depression is the explanation, but may be more likely to investigate if someone is anxious because they think it will reassure them. These are conjectures but they would fit with the data.’
The researchers point out that the results should be considered in conjunction with other evidence suggesting a variety of adverse physical health outcomes and poor health associated with mental disorders such as depression and psychotic disorders.
In light of the findings, Dr Stewart makes suggestions on the focus of future developments in the treatment of depression and anxiety: ‘The physical health of people with current or previous mental disorder needs a lot more attention than it gets at the moment.
‘This applies to primary care, secondary mental health care and general hospital care in the sense that there should be more active screening for physical disorders and risk factors, such as blood pressure, cholesterol, adverse diet, smoking, lack of exercise, in people with mental disorders. This should be done in addition to more active treatment of disorders when present, and more effective general health promotion
http://www.sciencedaily.com/releases/2009/11/091117094933.htm

Breakfast-not later than 7 am,Lunch-not later than 1 pm,Dinner-not later than 10 pm.
Breakfast must be heavy;avoid drinking water during meals.Fill the stomach half part,1/4 water,leave 1/4 empty.Avoid oil in breakfast.
Lunch must have leafy vegetables,nothing should be deep fried,oil to be used minimally,use spice rarely,drink butter milk,minimal use of meat and root vegetables.
Dinner-avoid milk products and curds and desserts like ice cream.
Do not engage in conversation while eating.( Source;Indian food habits as per Smriti)
Take fruits in empty stomach.
ScienceDaily (Nov. 26, 2009) — When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands of genes in the liver — the body’s metabolic clearinghouse — is mostly controlled by food intake and not by the body’s circadian clock as conventional wisdom had it.
See Also:

“If feeding time determines the activity of a large number of genes completely independent of the circadian clock, when you eat and fast each day will have a huge impact on your metabolism,” says the study’s leader Satchidananda (Satchin) Panda, Ph.D., an assistant professor in the Regulatory Biology Laboratory.
The Salk researchers’ findings, which will be published in a forthcoming issue of the Proceedings of the National Academy of Sciences, could explain why shift workers are unusually prone to metabolic syndrome, diabetes, high cholesterol levels and obesity.
“We believe that it is not shift work per se that wreaks havoc with the body’s metabolism but changing shifts and weekends, when workers switch back to a regular day-night cycle,” says Panda.
In mammals, the circadian timing system is composed of a central circadian clock in the brain and subsidiary oscillators in most peripheral tissues. The master clock in the brain is set by light and determines the overall diurnal or nocturnal preference of an animal, including sleep-wake cycles and feeding behavior. The clocks in peripheral organs are largely insensitive to changes in the light regime. Instead, their phase and amplitude are affected by many factors including feeding time.
The clocks themselves keep time through the fall and rise of gene activity on a roughly 24-hour schedule that anticipates environmental changes and adapts many of the body’s physiological function to the appropriate time of day.
“The liver oscillator in particular helps the organism to adapt to a daily pattern of food availability by temporally tuning the activity of thousands of genes regulating metabolism and physiology,” says Panda. “This regulation is very important, since the absence of a robust circadian clock predisposes the organism to various metabolic dysfunctions and diseases.”
Despite its importance, it wasn’t clear whether the circadian rhythms in hepatic transcription were solely controlled by the liver clock in anticipation of food or responded to actual food intake.
To investigate how much influence rhythmic food intake exerts over the hepatic circadian oscillator, graduate student and first author Christopher Vollmers put normal and clock-deficient mice on strictly controlled feeding and fasting schedules while monitoring gene expression across the whole genome.
He found that putting mice on a strict 8-hour feeding/16-hour fasting schedule restored the circadian transcription pattern of most metabolic genes in the liver of mice without a circadian clock. Conversely, during prolonged fasting, only a small subset of genes continued to be transcribed in a circadian pattern even with a functional circadian clock present.
“Food-induced transcription functions like a metabolic sand timer that runs for 24 hours and is continually reset by the feeding schedule while the central circadian clock is driven by self-sustaining rhythms that help us anticipate food, based on our usual eating schedule,” says Vollmers. “But in the real world we don’t eat at the same time every day and it makes perfect sense to increase the activity of metabolic genes when you need them the most.”
For example, genes that encode enzymes needed to break down sugars rise immediately after a meal, while the activity of genes encoding enzymes needed to break down fat is highest when we fast. Consequently a clearly defined daily feeding schedule puts the enzymes of metabolism in shift work and optimizes burning of sugar and fat.
“Our study represents a seminal shift in how we think about circadian cycles,” says Panda. “The circadian clock is no longer the sole driver of rhythms in gene function, instead the phase and amplitude of rhythmic gene function in the liver is determined by feeding and fasting periods — the more defined they are, the more robust the oscillations become.”
While the importance of robust metabolic rhythms for our health has been demonstrated by shift workers’ increased risk of developing metabolic syndrome, the underlying molecular reasons are still unclear. Panda speculates that the oscillations serve one big purpose: to separate incompatible processes, such as the generation of DNA-damaging reactive oxygen species and DNA replication.
Panda, for one, has stopped eating between 8 pm and 8 am and says he feels great. “I even lost weight, although I eat whatever I want during the day,” he says.
Researchers who also contributed the work include postdoctoral researcher Luciano DiTacchio, Ph.D., graduate students Sandhyarani Pulivarthy and Shubhrox Gill, as well as research assistant Hiep Le, all in the Regulatory Biology Laboratory.
The work was funded in part by the National Institutes of Health and the Pew Scholars
Story Source:
Adapted from materials provided by Salk Institute.
http://www.sciencedaily.com/releases/2009/11/091125094321.htm

The point I’m making is this, and I hope you will think on this further if you are to have any hope of having a life again. Most things on this site are NOT a top secret and NOT above it or below it. Fact is, most of it doesn’t exist at all! The CIA or whatever government entity is all over this site and others like it. Injecting tid bits of World-Ending conspiracies to create fear in the herds of people who think they are getting to the “bottom of things”. And they have succeeded in lowering the vibrational state of the remaining smart people who learned that T.V. media is ful of B.S. Well…….GOTCHA!!!!

Stop listening to any news that is negative AT ALL. STOP listening or reading ANYTHING negative whatsoever and RAISE your bodily vibrations back to where it should be. The higher you vibrate, the closer you are to the source of white light that gives life to all. The angrier or depressed or agitated you are, the lower your body vibrates and the weaker you become. They are killing you from the inside out and you’re falling for it.

Please wake up, let go of your flesh and come to the light. There is much more in our world then what you see and touch. Don’t let them make you scared or angry at ANYTHING!

Anger, depression anxiety is Kryptonite my fellow humans.

I’m making my own little attempt on this site to save some lives. Brighten your vision and go back to loving everything in your life and loving your creator. You are not a monkey, and you’re not a mistake. The ancient civilizations have tried to communicate this to us, but our educational system has destroyed it’s importance.

Pull your kids out of public

In our indefatigable quest for enemies, Americans have now targeted the obese.

Even though I’m living in Australia, I can get the 6:30pm CBS News from America live at 11:30am the following day. And even though I’ll have read all the major news online, I like to watch the meagre 20 minutes of heavily scripted network news. It keeps me culturally and psychologically connected to home.

The format of network news is predictable: one political news item, one item on America’s health, and one fluff piece on an inspiring American, followed by a few quick words on the real domestic and international news to close the show. The meat is in the rear, and if you’re actually interested in news, you’ll sit through the formulaic bit and 10 minutes of commercials.

One of the health items last week was disturbing. In our debilitating but understandable anxiety about the economy, we’ve been frantically looking for the right donkey on which to pin the tail of guilt. We’ve been blaming Wall Street and Congress for a year now (and rightly so), but that hasn’t satisfied us, because the impact of the recession has only worsened. Now that healthcare reform is the item du jour, the current healthcare system has been targeted as one cause of our economic woes (and rightly so).  But now this begs the question, “How”?

Republicans and Democrats will never agree on who’s to blame within the system – insurance companies, drug companies, doctors, hospitals, or government bureaucrats. That leaves consensus on only one group to blame: patients.

CBS News and everyone else it seems, has now determined that the blame for our economic collapse and dysfunctional healthcare system can be confidently placed at the feet of America’s obese.

Shameful.

Prevalence of Obesity in America (CDC)

As a medical student, I’m fully aware of the health consequences of overweight and obesity. I’m just as aware of the health consequences of smoking, alcohol consumption, physical inactivity and poor eating habits among the skinny. I don’t deny that being obese places you at higher risk of a host of chronic diseases; but I do deny that obesity is the exclusive fault of the patients who suffer from the condition. And I further deny that the obese are principally responsible for the crippling expense of providing healthcare in America.

The reasons for the exorbitant cost of healthcare in America are multi-factorial. The reasons for obesity in America have as much if not more to do with the actions of government and industry than they do with the actions of people. Without any serious reflection on the subject – indeed, just considering America on my last trip home, a host of factors are implicated in the obesity epidemic.

City Planning: Good luck finding a sidewalk on any of the major roads in my family’s town. If you want to walk anywhere, be ready to get flattened by an SUV. And good luck finding any place to go within walking distance. Wal-Marts and supermarkets are built on giant lots at considerable distance from residential areas to accommodate their monolithic parking lots. And no, there are no bike lanes. Virginia ain’t San Francisco people. This is the fault of local government.

Work/Life Balance: You get the kids ready for school between 6 and 7; you’re on the road to work from 8 to 9; you’re sitting in a chair at work until 4 or 5; you’re on the road home from 5 to 6; you’re cooking dinner from 6 to 7; you’re socializing with the kids from 7 to 8; you’re getting the kids bathed and in bed from 8 to 9; and then you’ve got an hour to yourself in the evening to decompress. Then the weekends are spent driving your kids the considerable distance to football and soccer practice, karate class and birthday parties. When are you supposed to exercise? This is the fault of city planning and employer demands.

Food: Only in America are entire aisles each devoted to sugary cereals, sodas, potato chips, candy, and frozen dinners. The variety of preservative-filled junk is staggering. The amount of saturated fat, trans-fat, sugar and salt in each item sold in an American grocery store is nauseating.  It would take a mother a full weekend to read the nutrition labels on the backs of boxed and bagged foods in order to find enough healthy choices to fill a grocery cart. And it would take an upper middle class family to afford to limit their purchases to fresh fruit, vegetables and meats. This is the work of the food industry playing on the financial insecurity of families who need to feed and please the palates of a household.

Healthcare: If the average American could afford regular visits to a family doctor, insidious weight gain and early signs of obesity-related disease could be caught early, and patients could be counseled about the urgent actions needed to prevent chronic disease. When patients have strong, reliable relationships with doctors who have an interest in their overall health, they become more aware of their health (or lack there of) and  more motivated to improve it. They’ve got an educator. They’ve got a coach. They’ve got a partner. But most Americans don’t have a family doctor they can trust and afford.  That’s the fault of the healthcare system.

At the end of the day, sure, we’re all responsible for what we put in our bodies and the amount of energy we expend. So individuals are also responsible for the obesity epidemic. But we’ve got enablers, promoters and accomplices aplenty. I’m not saying anything new here. We know this. So let’s not forget this in our quest to find a scapegoat.

Because the scapegoats come in all shapes and sizes.

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In other CBS News, by way of evidence, a recent study has found:

A medium popcorn and soda combo from Regal, the country’s biggest movie chain, is the equivalent of eating three McDonald’s Quarter Pounders with 12 pats of butter. That’s 1,160 calories and three days worth – 60 grams – of fat.

So ends my 30-year tradition of eating popcorn at the movies.

Republican Senator Orrin G. Hatch (Utah)

“It’s going to be a holy war.” – Senator Orrin G. Hatch on the Republican fight against healthcare reform

NYT columnist Nicholas Kristof takes a short trip through the history of Republican opposition to social welfare programs. In The Wrong Side of History, he reminds us of the identical Republican arguments against Social Security and Medicare for the elderly.

Understanding past Republican opposition to these indispensable programs is critical to understanding their present fight against insuring 30-odd million people, including 8 million children.

And critical to understanding the feasibility of reform is an appreciation of universal health care’s success stories worldwide. Contrary to Republican claims, the British National Health Service (NHS) is a success. The Brits will whinge about it, sure, but universal health care in Britain works and works well. The British have a longer life expectancy than we do, and a lower infant mortality rate. And those are but two measures of success of their superior approach to public health.

And then there’s Australia, which you never hear about in the healthcare debate. While my relatives in America are terrified of losing their jobs because they’ll lose their health insurance, I reap the benefits from Australia’s universal healthcare system, Medicare. I see a family doctor on average four times a year, and he’s referred me to various specialists in the past 12 months alone. I had a minor surgical procedure earlier this year and will have another next month. The cost?  A pittance. Or free. The most important thing I need in my wallet when I visit the doctor is my Medicare card.

No one has to worry about losing their health insurance in Australia. Provided by the government, it’s the privilege of residency or citizenship. It’s also a reflection of a civilized and compassionate society, and one with the intelligence and foresight to recognize that a healthy citizenry cures economic and social ills.

No – more than that. Universal healthcare is also the height of patriotism; for how can one claim to love America, if one cares so little for the people who inhabit it? What is a nation but a community of souls with a vested interest in the productivity of each for the benefit of all? No community can thrive where its people are left to die by the roadside – at least not without losing its soul.

“It’s going to be a holy war” says Orrin Hatch, a fierce opponent to government-funded universal healthcare. As a senator, Hatch enjoys government-provided health insurance, and as a senior citizen, is eligible for government-funded Medicare. Well, let him fight for his god.

I’ll fight for Americans.