Blogs about: Homologous Recombination

Featured Blog

ATR and H2AX

Last month (December 2008)  in the Journal of Biological Chemistry, Rebecca Chanoux and colleagues reported the results of their studies on ATR and H2AX. They wrote: “If ATR prevents the collaps… more →

DRUSE

Double-strand break interacting RNAs (diRNAs)

biobabel wrote 1 year ago: A new role for small RNAs in the repair of DNA double-strand breaks has been reported in Cell. Wei e … more →

Tags: New Papers, RNA, double strand break, diRNA, Arabidopsis, DNA repair

PARP Inhibitor Olaparib Has Activity in High-Grade Serous Ovarian Cancer Without Inherited BRCA1 or BRCA2 Gene Mutations

Paul Cacciatore wrote 1 year ago: Researchers affiliated with the British Columbia Cancer Agency reported Phase 2 clinical study resul … more →

Tags: Clinical Trial Results, Novel Therapies, Pipeline Drugs, AZD2281, BRCA gene mutations, british columbia cancer agency, dna repair pathway, germline mutations, Karen A. Gelmon M.D.

A Step Toward a Cure for Cancer

Joogle wrote 2 years ago: Cancer is one of the leading diseases in which about 3,400 people are diagnosed with every day just … more →

Tags: Science, health, Other, Cancer, alt, Cure, liana organesian, telomere, Telomerase

PARP Inhibitor MK-4827 Shows Anti-Tumor Activity in First Human Clinical Study — 3 comments

Paul Cacciatore wrote 2 years ago: MK-4827, a new drug that targets proteins responsible for helping cancer cells repair their damaged … more →

Tags: Biological Therapies, Clinical Trial Results, Meeting Highlights, Novel Therapies, Pipeline Drugs, AACR, AstraZeneca, BRCA-1 gene, BRCA 2 gene

New Assay Test Predicts That 50% of Ovarian Cancers Will Respond To In Vitro PARP Inhibition

Paul Cacciatore wrote 2 years ago: U.K. researchers develop a new test that could be used to select ovarian cancer patients who will be … more →

Tags: Pipeline Drugs, Novel Therapies, Genetics, Medical Study Results, Preclinical Testing, Discoveries, biomarker, targeted therapies, AG-14699

ATR and H2AX

druse wrote 4 years ago: Last month (December 2008)  in the Journal of Biological Chemistry, Rebecca Chanoux and colleagues r … more →

Tags: Genetics, recombination, DNA, double strand break, Biochemistry, DNA repair, DNA damage, genome stability, H2A.X

human exonuclease 1 and BLM helicase

druse wrote 4 years ago: In a recent paper by Amitabh Nimonkar and colleagues, it was established that human BLM helicase, a … more →

Tags: Biology, Molecular Biology, Genetics, exonuclease, DNA, double strand break, Biochemistry, DNA repair, Helicase

WRN mini-review

druse wrote 4 years ago: In a recent issue of DNA Repair [7 (2008) 1776–1786], Julia Sidorova reviews the role of WRN in pres … more →

Tags: Science, ageing, aging, Biology, Molecular Biology, Genetics, Biological Sciences, Lifespan, exonuclease

Homologous Recombination in E coli

ajbedekar wrote 4 years ago: Homologous recombination is a native process in yeast and natural to viruses; however if one wishes … more →

Tags: strains, gene deletions

rDNA and recombination

druse wrote 4 years ago: In a mini-review by Ellen Tsang and Anthony Carr, recombination is highly regulated in the rDNA. Rep … more →

Tags: Science, ageing, aging, Biology, Molecular Biology, Genetics, recombination, DNA, Gene


Related Tags
All →

Follow this tag via RSS