Blogs about: Igf 1r
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Exelixis IGF-1R/Src inhibitor XL228 effective in Phase I
Phase I data presented at the EORTC-NCI-AACR Symposium show Exelixis’ IGF-1R/Src inhibitor XL228 to show signs of Clinical Benefit inpatients with advanced malignancies… more →
Kinase News
Exelixis IGF-1R/Src inhibitor XL228 effective in Phase I
crimsoncanary wrote 1 year ago: Phase I data presented at the EORTC-NCI-AACR Symposium show Exelixis’ IGF-1R/Src inhibitor XL … more →
Antisense Therapeutics IGF-1R agent ATL-1101 effective in vivo
crimsoncanary wrote 1 year ago: Antisense Therapeutic’s IGF-1R antisense product ATL1101 has been found to suppress tumor grow … more →
Roche to initiate Phase II trial of IGF-1R MAb R1507 in NSCLC
crimsoncanary wrote 1 year ago: Roche and Genmab are preparing to initatea phase II trial of IGF-1R MAb R1507 in NSCLC in combinatio … more →
ImClone initiate randomized Phase II trial of IMC-A12 in breast cancer
crimsoncanary wrote 1 year ago: ImClone Systems have initiated a phase II clinical trial of its anti-IGF-1R MAb IMC-A12 in women wit … more →
Pfizers IGF-1R MAb CP-751,871 effective in NSCLC
crimsoncanary wrote 1 year ago: Phase II data presented at the European of Medical Oncology (ESMO) show that Pfizer’s IGF-1R i … more →
Coadministration of IGF-1R inhibitor BMS-554417 with HER2 inhibitor BMS-599626 increases antiproliferative activity
crimsoncanary wrote 1 year ago: Co administration of IGF-1R inhibitor, BMS-554417 with HER2 inhibitor BMS-599626 resulted in a syner … more →
ImClone initate Phase II trial in prostate cancer comparing IMC-A12 and IMC-1121B
crimsoncanary wrote 1 year ago: ImClone have commenced enrollment in a Phase II trial with either IMC-A12 or IMC-1121B in patients w … more →
IGF-1R/FAK inhibitor TAE226 shows efficacy in preclinical studies
crimsoncanary wrote 1 year ago: Novartis’ FAK/IGF-1R inhibitor TAE226 has shown anti tumor activity in Barrett’s esophag … more →
ImClone initiate Phase II study of IGF-1R MAb for Advanced Soft Tissue Sarcoma
crimsoncanary wrote 1 year ago: ImClone Systems have announced the start of a Phase II clinical trial of IMC-A12, its IGF-1R monoclo … more →
Axelar initiate Phase I/II trial with IGF-1R drug AXL1717
crimsoncanary wrote 1 year ago: Axelar has initiated a Phase I/II clinical trial in cancer patients with its insulin-like growth fac … more →
ImClone begin trial of anti IGF-1R MAb IMC-A12 in combination with Temsirolimus
crimsoncanary wrote 1 year ago: ImClone have commenced a Phase 1 clinical trial of IGF-1R MAb in combination with mTOR inhibitor tem … more →
Pfizer present data on CP-751,871 in NSCLC
crimsoncanary wrote 1 year ago: Data presented at ASCO show Pfizer’s IGF-R1MAb CP-751,871 to demonstrate efficacy in non-small … more →
Phase I results of AVE1642 in patients with advanced solid tumors
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crimsoncanary wrote 1 year ago: Immunogen have presented Phase I data on its IGF-1R MAb AVE1642 as ASCO. The drug was found to be we … more →
Amgen present data on new kinase programs
crimsoncanary wrote 1 year ago: AMG-479 – IGF-1R MAb – Phase I results show the drug is safe when administered in combin … more →
IMC-A12 enters Phase II in Advanced Liver Cancer
crimsoncanary wrote 1 year ago: ImClone’s IGF-1R receptor MAb has entered Phase II trials for Advanced Liver Cancer. It is alr … more →
