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Blogs about: Ion Channel

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ASIC1a and the fear of drowning

dendrite wrote 1 week ago: Image by Sbrimbillina via Flickr Here’s a gene whose relationship to mental function is very s … more →

Tags: amygdala, ASIC1a, acid, Blood+, carbon dioxide, drowning, Emotion, Fear, Gene expression

Enlarged prostate surgery

capros wrote 1 year ago: Should I Get Surgery for My Enlarged Prostate? The key factor in determining whether you should have … more →

Tags: Living with Prostate Cancer, prostate massage, prostate cancer resource, prostatectomy, Urology, Hereditary, Enlarged prostate surgery

Evotec/Pfizer initiate Phase I trial of VR1 antagonist

crimsoncanary wrote 1 year ago: Evotec AG have announced the initiation of a Phase I clinical trial of a small molecule VR1 (vanillo … more →

Tags: Antagonist, Pfizer, TRPV1, Vanilloid, Evotec, Phase I, vanilloid 1

Inspire modifies denufosol Phase III trial for Cystic Fibrosis

crimsoncanary wrote 1 year ago: Inspire Pharmaceuticals have announced modifications to the clinical protocol for TIGER-2, the Compa … more →

Tags: agonist, denufosol, INS-37217, INS37217, P2Y2, Purinoreceptor P2Y2, Inspire, Purinoreceptor

Anesiva insitate Phase II trual of Adlea in Arthroscopic Shoulder Surgery

crimsoncanary wrote 1 year ago: Anesiva have begun a Phase II clinical trial of Adlea, the company’s long-acting capsaicin product i … more →

Tags: agonist, Anesiva, TRPV1, Vanilloid, VR1, Adlea, ALGRX-4975, phase ii, ALGRX4975

NeurogesX Initiate Phase I of NGX-1998 Capsaicin Liquid Formulation

crimsoncanary wrote 1 year ago: NeurogesX has initiated a Phase 1 clinical trial of NGX-1998, a high-concentration, capsaicin-based … more →

Tags: agonist, TRPV1, Vanilloid, NeurogesX, Capsaicin, NGX-1998, NGX1998

Vertexs VX-770 improves lung function in cystic fibrosis

crimsoncanary wrote 1 year ago: Data presentes at the 31st European Cystic Fibrosis Society Meeting shows Vertex’s VX-770 to i … more →

Tags: chloride channel, cl channel, cftr, Vertex, Chlorine channel

AstraZeneca and Cellectricon collaborate on Dynaflow High Throughput Ion Channel Screening

crimsoncanary wrote 1 year ago: AstraZeneca have expanded their collaboration with Cellectricon. AstraZeneca will install two Dynafl … more →

Tags: Research, AstraZeneca, Cellectricon

Inspire’s Denufosol shows efficacy in Phase III trials in Cystic Fibrosis

crimsoncanary wrote 1 year ago: Inspire’s denufosol inhalation solution has shown efficacy in Phase III trials in Cystic Fibrosis. F … more →

Tags: agonist, denufosol, INS-37217, INS37217, P2Y2, Purinoreceptor P2Y2, Inspire

Phase II trials of Adlea in post orthopedic surgery pain to take place in South Korea

crimsoncanary wrote 1 year ago: Anesiva to begin Phase II trial of Capsaicin drug Adlea for use in the treatment of post orthopedic … more →

Tags: agonist, Anesiva, TRPV1, Vanilloid, VR1, Adlea, ALGRX-4975, phase ii

NeurogesX submit IND for liquid formulation of Capsaicin, NGX-1998

crimsoncanary wrote 1 year ago: NeurogesX have submitted an IND for the liquid formulation of Capsaicin, NGX-1998 for the treatment … more →

Tags: agonist, TRPV1, Vanilloid, NeurogesX, Regulatory, VR1

US and WO patent update for the week ending 05/23

crimsoncanary wrote 1 year ago: US and WO ion channel patents have been updated for this week at IonChannelCentral.com … more →

Tags: Patents

TRPV4 Channel Agonist GSK1016790A Induces Urinary Bladder Contraction and Hyperactivity

crimsoncanary wrote 1 year ago: GSK’s transient receptor potential vanilloid 4 (TRPV4) agonist GSK1016790A contracts mouse bla … more →

Tags: agonist, TRPV4, GSK1016790A, GSK-1016790A, 1016790, GSK, GlaxoSmithKline

Dendreons TRPM8 modulator D3263 shows promise in BPH

crimsoncanary wrote 1 year ago: Dendreon’s TRPM8 modulator D-3263 has been shown to reduce prostate weight by 39% in an animal … more →

Tags: TRPM8, D3263, D-3263, dendreon

Amitiza (lubiprostone) relieves IBS in Phase III

crimsoncanary wrote 1 year ago: Chloride channel agonist Amitiza (lubiprostone) had been shown to significantly relieve symptoms of … more →

Tags: Sucampo, Takeda, amitiza, CIC-2, CIC2, chloride channel, cl channel, lubiprostone, RU-0211

YM-758 pharmacokinetics in rats and humans

crimsoncanary wrote 1 year ago: The hepatic uptake and excretion of YM-758 is otlined in a Drug Metabolism and Disposition paper. YM … more →

Tags: Calcium Channel, ca channel, YM-758, YM758, Astellas

US and WO patent update for the week ending 05/16

crimsoncanary wrote 1 year ago: US and WO ion channel patents have been updated for this week at IonChannelCentral.com … more →

Tags: Patents

Azor shows efficacy in difficult to treat patient groups

crimsoncanary wrote 1 year ago: Data presented at ASH shows that Azor (amlodipine and olmesartan medoxomil) safely and effectively l … more →

Tags: Calcium Channel, ca channel, Antagonist, amlodipine, Angiotensin II AT1, azor, Daiichi Sankyo, Olmesartan, Trials

Exforge treatment effective in black patients

crimsoncanary wrote 1 year ago: Black patients treated with Exforge (Amlodipine/Valsartan) have been show to experience a significan … more →

Tags: Calcium Channel, ca channel, amlodipine, Copalia, Dafiro, Exforge, GPCR, Imprida, novartis


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