Blogs about: Neurobiochemistry

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Milestone: The X-ray Crystal structure of the voltage gated sodium channel

brainchemist wrote 1 year ago: The crystal structure of a voltage-gated sodium channel Jian Payandeh, Todd Scheuer, Ning Zheng … more →

Combining Crystallography and Physical Chemistry (FRET) to study the conformations of fast excitatory AMPA receptors

brainchemist wrote 2 years ago: FRET = single-molecule fluorescence resonance energy transfer Structural landscape of isolated agoni … more →

Tags: fret, AMPA receptors, crystallography, conformations

Cognition enhancement strategies

brainchemist wrote 2 years ago: Cognition enhancement strategies. J Neurosci. 2010 Nov 10;30(45):14987-92. Bibb JA, Mayford MR, Tsie … more →

Tags: Neurotherapy, NMDA, Cognition Enhancement, protein translation, Protein degradation, cytoskeletal dynamics, extracellular matrix interactions, receptor trafficking, synaptic remodeling

α-Synuclein protein advances Parkinson's by preventing neurons from clearing debris

brainchemist wrote 2 years ago: α-Synuclein impairs macroautophagy: implications for Parkinson’s disease JCB Home > 2010 Archive … more →

Tags: Parkinson's, synuclein, Autophagy

Molecular Basis of Plasticity: SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

brainchemist wrote 2 years ago: Neurons that fire together wire together. Adhesion molecule SynCAM1: promotes new synapses in the de … more →

Tags: Learning, PLASTICITY, synaptogenesis, SynCAM1, adhesion molecule, mice, long-term depression, Spatial Learning, neurites

Axon and target communicate to organize synaptic differentiation.

brainchemist wrote 2 years ago: Key Presynaptic organizers: NT-7a, neuroligin, synaptic cell adhesion molecule (SynCAM) and fibrobla … more →

Tags: synapse, PLASTICITY, SynCAM, FGF-22, NARP, ephrinB, WNT-7a, neuroligin, neurexin

Neurogenesis in the adult human hippocampus

brainchemist wrote 2 years ago: Neurogenesis in the adult human hippocampus Nature Medicine 4, 1313 – 1317 (1998) doi:10.1038/ … more →

Tags: hippocampus, Dentate gyrus, bromodeoxyuridine, Neurogenesis, S Phase, neuron specific enolase, neun, calbindin

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

brainchemist wrote 2 years ago: Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus Nature Neuros … more →

Tags: Exercise, Running, Learning, Dentate gyrus, Social Interaction, physical activity, bromodeoxyuridine, Neurogenesis

Pain: Sites of Origin, Pathways, and Neurotransmitters

brainchemist wrote 2 years ago: Pain: Sites of Origin, Pathways, and Neurotransmitters Source: Canadian Council on Animal Care The p … more →

Tags: Pain, Blood Pressure, Respiration, thalamus, NT, reticular formation, arousal, Heart Rate, Hypersensitivity

Investigating the neurobiology of music: BDNF modulation in the hippocampus of young adult mice.

brainchemist wrote 2 years ago: Investigating the neurobiology of music: brain-derived neurotrophic factor modulation in the hippoca … more →

Tags: Music, BDNF, Music 2, mood disorder, NGF, Mood, dementia, Parkinson's, Learning

Music exposure differentially alters the levels of brain-derived neurotrophic factor and nerve growth factor in the mouse hypothalamus1 comment

brainchemist wrote 2 years ago: Music exposure differentially alters the levels of brain-derived neurotrophic factor and nerve growt … more →

Tags: Music, BDNF, Depression, hypothalamic pituitatry adrenocortical axis, mood disorder, anxiety, NGF, hypothalamus, Homeostasis

Anxiolytic effect of music exposure on BDNFMet/Met transgenic mice.

brainchemist wrote 2 years ago: Anxiolytic effect of music exposure on BDNFMet/Met transgenic mice. Brain Res. 2010 Aug 6;1347:71-9. … more →

Tags: Music, amygdala, anxiety, BDNF, hippocampus, Music 2, prefrontal cortex, serotonin, SSRI

BDNF as a biomarker for mood disorders: an historical overview and future directions.

brainchemist wrote 2 years ago: Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and futu … more →

Tags: BDNF, Depression, Review, mood disorder, Bipolar Disorder, Major Depressive Disorder, biomarker

Brain connections have rhythm: Circadian and Homeostatic Regulation of Structural Synaptic Plasticity in Hypocretin Neurons @ STANFORD

brainchemist wrote 2 years ago: Circadian and Homeostatic Regulation of Structural Synaptic Plasticity in Hypocretin Neurons Lior Ap … more →

Tags: rhythm, sleep, Hypocretin, orexin, HCRT, nptx2b

Stunning Details of Brain Connections: Single-Synapse Analysis of a Diverse Synapse Population: Proteomic Imaging Methods and Markers @ STANFORD

brainchemist wrote 2 years ago: Journal Reference: Kristina D. Micheva, Brad Busse, Nicholas C. Weiler, Nancy O’Rourke, Stephe … more →

Tags: neuroimaging, array tomography, synapse, stanford

Neurobiochemical Foundations of Sleep: ATP and the purine type 2 X7 receptor affect sleep

brainchemist wrote 2 years ago: Abstract Sleep is dependent upon prior brain activities, e.g., after prolonged wakefulness sleep reb … more →

Tags: sleep, insomnia, ATP, Cytokines, REM, P2X7

Pleasurable food Reduces Stress

brainchemist wrote 2 years ago: ScienceDaily (Nov. 12, 2010) — Whether it’s food or sex, pleasurable activity provides more th … more →

Tags: Stress, comfort food, Taste, hypothalamic pituitatry adrenocortical axis, basolateral amygdala, MRNA

The See-Saw Circuit of Fear: Genetic dissection of an amygdala microcircuit that gates conditioned fear

brainchemist wrote 2 years ago: ABSTRACT The role of different amygdala nuclei (neuroanatomical subdivisions) in processing Pavlovia … more →

Tags: Music, Music 2, Fear, amygdala, Microcircuit

TED TALK: Understanding the brain by controlling neurons - Gero Miesenboeck reengineers a brain

brainchemist wrote 2 years ago: TED TALK Gero Miesenboeck reengineers a brain Optical mind control. In this case the brain is contro … more →

Tags: Seminar, ted-talk, Gerome Miesenboeck, Drosophila, critic, Actor, Optogenetics, Behavior


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