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Predicting PARADIGM-HF, Or What To Expect When You're Expecting

The wait is almost over. For the last 5 months the most eagerly awaited trial in the cardiovascular universe has been PARADIGM-HF, the large (8,500 patient) trial of a new and novel heart failure drug from Novartis. 75 more words

People, Places & Events

Rise In Popularity Of E-Cigarettes Sparks Concerns And Recommendations

The recent dramatic rise in popularity of e-cigarettes threatens to reverse hard-fought progress in the war against smoking, according to a new policy statement from the American Heart Association… 55 more words

Policy & Ethics

Why Guidelines Should Be Waged Like War

Here’s a modest proposal: we need fewer and shorter guidelines. In fact, I’d like to propose that guidelines, like war, should be waged only when there is absolute consensus and overwhelming evidence. 32 more words

Policy & Ethics

US Department Of Justice Ends Investigation Of AstraZenca Trial

AstraZeneca announced today that the US Department of Justice has ended its investigation into alleged misconduct associated with the pivotal PLATO trial. The company said it had fully cooperated with the investigation, which began in October of 2013. 10 more words

Policy & Ethics

An Old Study Fuels Debate Over Blood Pressure Guidelines

In the last year new guidelines relating to cardiovascular disease have been the subject of intense criticism and debate. The status of the blood pressure guidelines has been particularly contentious, since several different groups have published contradictory guidelines, while several authors of the most prominent group, the Eighth Joint National Committee, published an impassioned dissent from their own published guideline. 92 more words

Policy & Ethics

An Expert's Perspective: Why Salt Is Not Like Tobacco And Why Guidelines Are Tricky

At the center of this week’s renewed debate on salt was Salim Yusuf, the long influential and often controversial cardiology researcher and clinical trialist based at McMaster University in Hamilton, Ontario. 106 more words

Policy & Ethics

New Studies Fuel The Debate Over Sodium

Three papers and an editorial in the New England Journal of Medicine are sure to throw fresh fuel on the ongoing fiery debate over sodium recommendations.  64 more words

Policy & Ethics