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Blogs about: Pharmacogenetics

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Avoid Coadministration of Clopidogrel [Plavix] and Omeprazole [Prilosec] or Esomeprazole [Nexium]

thassodotcom wrote 2 weeks ago: November 17, 2009 – Today, the US Food and Drug Administration (FDA) informed on new data show … more →

Tags: Drug/Drug Interaction, Allelic Variants, Cimetidine [Tagamet], Clopidogrel [Plavix], Cyp2C19, CYP2C19*2, CYP2C19*3, CYP2C19*4, CYP2C19*5

The NFCR co-authored this press release to help raise awareness if tamoxifen DNA testing

DNADiva wrote 1 month ago: (SEATTLE) – Five hundred thousand women in the U.S. are taking tamoxifen to prevent breast cancer re … more →

Tags: Personalized Medicine, breast cancer, CYP2D6

It's Time for Tamoxifen CYP2D6 Testing to Become the Standard of Care

DNADiva wrote 1 month ago: JAMA released more research today that further confirms the importance of CYP2D6 testing to determin … more →

Tags: Personalized Medicine, breast cancer, CYP, CYP2D6, Cytochrome, JAMA, tamoxifen

Individual results may vary

Suchita S wrote 2 months ago: That phrase often appears in the fine print on TV commercials for prescription drugs or in magazine … more →

Tags: Suchita S, Medical School, Medicare, Tobacco Companies, Pharmaceuticals, FDA, Genetics, Tobacco, Pharmacology

OurBlook Interview: Creating Tailor-Made Prescriptions for All Patients

DNADiva wrote 2 months ago: Ashcraft: Creating Tailor-Made Prescriptions for All Patients Kristine Ashcraft, director of sales a … more →

Tags: Personalized Medicine

Health Canada: Important New Safety Information on Potential Interactions of Proton Pump Inhibitors (PPIs) with Clopidogrel [Plavix]

thassodotcom wrote 3 months ago: August 21, 2008 -  From a new posting on Health Canadas’s website, we learn that in collaboration wi … more →

Tags: Drug/Drug Interaction, Health Canada, Clopidogrel [Plavix], Cyp2C19, Prodrug

Gene May Predict Response to Hepatitis C Therapy

thassodotcom wrote 3 months ago: August 18, 2008 – A slight difference in a person’s genetic code could determine whether … more →

Tags: genetic susceptibility, New research, Hepatitis C, Peginterferon, Hepatitis C Virus (HCV), ribavirin

Michael Jackson’s Death Illustrates the Danger of Adverse Drug Reactions1 comment

DNADiva wrote 4 months ago: The tragic death of Michael Jackson has the potential to create an important “learning moment … more →

Tags: Cytochrome P450, drug interactions, Personalized Medicine, ADRs, adverse drug reactions, MICHAEL JACKSON, pharmacovigilance

New study suggests better ROI for pretreatment CYP2D6 screening

DNADiva wrote 6 months ago: Pharmacogenomics J. 2009 May 19. Intermediate metabolizer: increased side effects in psychoactive dr … more →

Tags: Personalized Medicine, 2Dy, CYP2D6, Cytochrome

Exploiting pharmacogentics and pharmacogenomics: From promise to pragmatic policies.

stanwolf wrote 8 months ago: Hopkins, MM., Ibarreta, D., Gaisser, S., Enzing, CM., Ryan, J., Martin, PA., Lewis, G., Detmar, S., … more →

Tags: Papers, Publications (2006), Policy, expectations, Pharmacogenomics

Realising the potential of genomic medicine.

stanwolf wrote 8 months ago: Martin, P.A. and Morrison, M., 2006. Realising the potential of genomic medicine. Available online. … more →

Tags: Reports, Publications (2006), expectations, patients, Pharmacogenomics

The promise of pharmacogenetics: assessing the prospects for disease and patient stratification.

stanwolf wrote 8 months ago: Smart, A. and Martin, P., 2006. The promise of pharmacogenetics: assessing the prospects for disease … more →

Tags: Papers, Publications (2006), Industry, commercialisation, drugs, Markets, Innovation, patients, Pharmacogenomics

False Positive? Prospects for the clinical and commercial development of pharmacogenetics.

stanwolf wrote 8 months ago: Martin, P.A., Smart, A., Lewis, G. and Webster, A., 2005. False Positive? Prospects for the clinical … more →

Tags: Publications (2005), commercialisation

Tailored Medicine: Whom Will it Fit? The Ethics of Patient and Disease Stratification.

stanwolf wrote 8 months ago: Smart, A., Martin, P. and Parker, M., 2004. Tailored Medicine: Whom Will it Fit? The Ethics of Patie … more →

Tags: Papers, Publications (2004), Disease, patients, tailored medicine

Integrating pharmacogenetics into society: in search of a model.

stanwolf wrote 8 months ago: Webster, A., Martin, P., Lewis, G. and Smart, A., 2004.Integrating pharmacogenetics into society: in … more →

Tags: Papers, Publications (2004), elsi, Policy, expectations

The drugs don’t work: expectations and the shaping of pharmacogenetics.

stanwolf wrote 8 months ago: Hedgecoe, A. and Martin, P., 2003. The drugs don’t work: expectations and the shaping of pharmacogen … more →

Tags: Papers, Publications (2003), elsi, socio-technical network, drugs, expectations

Decreased Susceptibility of the Cytochrome P450 2B6 Variant K262R to Inhibition by Several Clinically Important Drugs.1 comment

DNADiva wrote 11 months ago: Drug Metab Dispos. 2008 Dec 12 Talakad JC, Kumar S, Halpert JR. University of California San Diego. … more →

Tags: Cytochrome P450, Personalized Medicine, Cytochrome, cytochromes

Mayo study further confirms the importance of CYP2D6 for tamoxifen effectiveness building the case for genotyping and medication management

DNADiva wrote 11 months ago: Mayo gave a presentation yesterday at the 31st annual San Antonio Breast Cancer Symposium that furth … more →

Tags: Cytochrome P450, drug interactions, Personalized Medicine, breast cancer, CYP2D6, Cytochrome, genotyping, persoanlized medicine, tamoxifen

Warfarin Pharmacogenetics: The Biochemistry1 comment

sciphu wrote 1 year ago: Image via Wikipedia Warfarin (marketed under brand names like Coumadin, Jantoven, Marevan, and Waran … more →

Tags: Coagulation, vitamin k, warfarin


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