Blogs about: Pi3k
Featured Blog
Exelixis PI3K Inhibitor XL147 effective in Phase I
Phase I data presented at the EORTC-NCI-AACR Symposium show Exelixis PI3K inhibitor XL147 to exhibit ‘robust pharmacodynamics’ and preliminary clinical benefit… more →
Kinase News
Friday Science Review: November 20, 2009
RChan wrote 1 month ago: Intestinal disease genomics and how hedgehogs cause arthritis… Genetic Clues to ‘Belly Aches’ … more →
AZ's got PI3K
— 3 comments
kinasepro wrote 4 months ago: WO/2009/093972 reminds you of… … more →
Pi3k @ Bayer
— 1 comment
kinasepro wrote 4 months ago: This one hones in on the sulphonamides: (from the former site in CT) WO/2009/091550; They stuck morp … more →
Prostaglandin signaling promotes neuroinflamation
annalsofneurology wrote 6 months ago: Opposite to previously reported results, Yao and colleagues demonstrate that prostaglandin E2 (PGE … more →
Keryx: Another beneficiary of the ASCO-effect
Michael Becker wrote 6 months ago: By Michael D. Becker In my prior article, I highlighted the “ASCO-effect,” which relates to the fact … more →
Best place to hide a PI3K review?
— 1 comment
kinasepro wrote 11 months ago: Somewhere like Biochimica et Biophysica Acta sure would do the trick. You could also try and bury on … more →
Exelixis PI3K Inhibitor XL147 effective in Phase I
crimsoncanary wrote 1 year ago: Phase I data presented at the EORTC-NCI-AACR Symposium show Exelixis PI3K inhibitor XL147 to exhibit … more →
Exelixis PI3K/mTOR Inhibitor XL765 effective in Phase I
crimsoncanary wrote 1 year ago: Phase I data presented at the EORTC-NCI-AACR Symposium show Exelixis PI3K/mTOR kinase inhbitor XL765 … more →
WO/2008/124161
kinasepro wrote 1 year ago: Exel’s got Pi3K-a in combination: Reminds one of the XL-147 combo study. So thats XL-647 ? I … more →
US20080255162
kinasepro wrote 1 year ago: Pfizer’s got PI3K: previously: … more →
Plethora 'o' PDB's
kinasepro wrote 1 year ago: GSK’s AKT stuff: 3d0e, 3E8D, 3E87, 3E88; J Med Chem, KP SGX: Jak2 3E64, 3E63, 3E62, BMCL Shoka … more →
Oncalis license PI3K inhibitors from ChemDiv
crimsoncanary wrote 1 year ago: Oncalis have entered in to an agreement to licence PI3K inhibitors, including ONC-201 from ChemDiv … more →
A new PI3K PDB
kinasepro wrote 1 year ago: UCB published they’re spin on LY-294002: 3DPD: BMCL see also: 1E7V … more →
Oncothyreon focus development on PI3K and HIF inhibitor
crimsoncanary wrote 1 year ago: Oncothyreon have announced plans to prioritize resources on the clinical development of PI3K inhibit … more →
Piramed/Genentech publish data on PI3K inhibitor GDC-0941
crimsoncanary wrote 1 year ago: Piramed/Genentech have published research leading to the development of lead compound GDC-0941 … more →
Semafores PI3K inhibitor SF1126 effective in vitro
crimsoncanary wrote 1 year ago: Data presented at the Seventh International Congress on Targeted Therapies in Cancer show Semafore … more →
Semafore present data on PI3K inhibitors
crimsoncanary wrote 1 year ago: Data presented at the Seventh International Congress on Targeted Therapies in Cancer detailed Semafo … more →
UCB describe series of PI3K inhibitors
crimsoncanary wrote 1 year ago: UCB have published a paper detailing the optimization of multi-isoform PI3 kinase inhibitors … more →
Novartis PI3K/mTOR inhibitor NVP-BEZ235 inhibit VEGF induced Angionesis/Cell proliferation
crimsoncanary wrote 1 year ago: Novartis’ dual PI3K/mTOR inhibitor NVP-BEZ235 has been found to inhibit VEGF-induced cell prol … more →
