Tags » Adjuvant

PORTOS: a gene signature that predicts salvage radiation success

Salvage radiation is curative in roughly half of all cases. There are many factors that contribute to an unfavorable prognosis, including waiting too long, high PSA and rapid PSA doubling time, adverse post-surgery pathology (stage, Gleason score, positive margins), and high Decipher or CAPRA-S scores. 1,754 more words

Treatment

Does adding an aspirin improve outcomes to treatment for localized prostate cancer?

The clinical research community in the UK (with access to relevant government funding) still appears to be able to do the types of trial of older drugs that would rarely if ever get done here in America today. 477 more words

Management

Urinary and sexual healing improved by waiting to start salvage radiation

Salvage radiation adds to the side effects of surgery and may halt the progress made towards healing. Healing takes time. On the other hand, we have learned that adjuvant or early salvage radiation has better oncological outcomes than waiting, the earlier the better ( 425 more words

Management

Very early salvage radiation has up to fourfold better outcomes and saves lives

Another subject that has come up a lot recently is when to have salvage radiation. It is always a pressing decision for those 30 percent of prostatectomy patients who have detectable PSA after prostatectomy. 813 more words

Management

How early salvage radiation therapy can be used to prevent metastases and save lives

Several clinical trials have established that adjuvant radiation reduces the risk of biochemical recurrence, but only one trial looked at and demonstrated an improvement in metastasis-free survival and prostate cancer-specific survival. 748 more words

Management