Tags » Allergy

Gene therapy for primary immune deficiencies: a Canadian perspective

The use of gene therapy (GT) for the treatment of primary immune deficiencies (PID) including severe combined immune deficiency (SCID) has progressed significantly in the recent years. 7 more words

By Alexandros G. Sfakianakis

Interleukin 21 inhibits cancer-mediated FOXP3 induction in naïve human CD4 T cells

Abstract

              <p>IL-21 is known to promote anti-tumour immunity due to its ability to promote T cell responses and counteract Treg-mediated suppression. It has also been shown to limit Treg frequencies during tumour-antigen stimulations. 158 more words
By Alexandros G. Sfakianakis

Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site

Abstract

              <p>Stimulator of IFN genes (STING) spontaneously contributes to anti-tumor immunity by inducing type I interferons (IFNs) following sensing of tumor-derived genomic DNAs in the tumor-bearing host. 319 more words
By Alexandros G. Sfakianakis

Pronounced effect of hapten binding on thermal stability of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain

Publication date: May 2017
Source:Molecular Immunology, Volume 85
Author(s): Yusui Sato, Satomi Inaba, Harumi Fukada, Takachika Azuma, Masayuki Oda
Immune response to T-cell-dependent antigens is highly dynamic; several B-cell clones responsible for antibody production appear alternately during immunization. 205 more words

By Alexandros G. Sfakianakis

Dietary intake is associated with respiratory health outcomes and DNA methylation in children with asthma

Asthma is an increasingly common chronic disease among children, and data point toward a complex mechanism involving genetic, environmental and epigenetic factors. Epigenetic modifications such as DNA hypo- or…

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By Alexandros G. Sfakianakis

Three Types of Reactions to Food

Posted by Colleen

Did you know that there are 3 types of reactions to food in which your immune system accidentally identifies the protein of that food and thinks it’s an enemy and attacks it? 248 more words

10 Quick Tips for those Living with Food Allergies.

  1. Read the ingredients (on absolutely everything!)

    I’m going to start with this basic tip. I know this may sound like the most obvious thing, especially if you’re an old pro on living with an allergy.

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Allergy