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REST is lost in mild cognitive impairment and Alzheimer’s disease

Human neurons are functional over an entire lifetime, yet the mechanisms that preserve function and protect against neurodegeneration during ageing are unknown.

A study shows that induction of the repressor element 1-silencing transcription factor (REST; also known as neuron-restrictive silencer factor, NRSF) is a universal feature of normal ageing in human cortical and hippocampal neurons. 693 more words


Brain Bleeding Risk for Men With Alzheimer’s Gene

Even though women for ApoE4 are at a higher risk for Alzheimer’s, men who have the gene and disease suffer more tiny hemorrhages in their brains. 1,013 more words


Addressing an Aging Population

Report highlights coffee’s potential role in reducing cognitive decline

Moderate coffee consumption (3-5 cups per day) may protect against age-related cognitive decline and related neurodegenerative diseases such as Alzheimer’s and Parkinson’s, according to  219 more words


How to register for The Longest Day

To get started, select an activity you love

Choose something you love — or honor a caregiver, someone living with Alzheimer’s, or someone you’ve lost by selecting his or her favorite hobby. 160 more words

Walk To End Alzheimer's

Lessons From Alzheimer's

Welcome to Lessons from Alzheimer’s. I have learned so many valuable lessons from my own personal experience with Alzheimer’s Disease. It was a hard and difficult journey for myself and my family. 90 more words

Alzheimer's Disease

Alzheimer’s disease: Have we lost our way?

My mother developed Alzheimer’s late in life, and just around the time when the first generation of Alzheimer’s drugs were being approved. These drugs help preserve function for a while, but only delay the inevitable. 593 more words


Alzheimer’s Plaques Reduced by Targeting Sugar Attachment to the BACE1 Enzyme

Researchers at the RIKEN-Max Planck Joint Research Center in Japan have demonstrated that hallmark symptoms of Alzheimer’s disease can be reduced when sugars are prevented from binding to one of the key enzymes implicated in the disease. 975 more words