Tags » Bisphosphonates

Atypical Femoral Fractures: An Update

We posted our first “Case Connections” article about  bisphosphonate-related atypical femoral fractures (AFFs) one year ago. Since then, JBJS Case Connector has published three additional case reports on the same topic, suggesting that it’s… 40 more words

Need To Know

Polymer-drug complex shines as a potential anti-osteoporosis drug

Osteoporosis is marked by loss of bone tissue and low bone mass leading to major physiological changes rendering it porous and brittle. It is a major health concern in developed countries, affecting 30% of women especially during postmenopausal age and 20% of men worldwide. 348 more words


Osteoporosis Drugs Not Effective as Claimed

Drugs being prescribed for osteoporosis, bisphosphonates, are not worth the cost and risk of side effects, according to a paper published in the British Medical Journal which analyzed data from 33 previous studies. 214 more words

Injury Treatment

Bisphosphonates for the prevention and treatment of osteoporosis

Osteoporosis is a systemic skeletal disorder characterized by bone loss, which leads to impaired bone strength and an increased risk of fractures. Two million fractures are attributed to osteoporosis annually in the United States and they are associated with serious morbidity and mortality. 124 more words

03 (October 2015)

Bisphosphonates Curb Bones Breaks in Women With T2D

Bisphosphonate therapy was effective for reducing fracture incidence among postmenopausal women with diabetes, a post hoc analysis of randomized trial data found.

Among women with diabetes, the relative risk of nonvertebral fracture was 0.52 (95% CI 0.33-0.80) and the relative risk of morphometric vertebral fracture was 0.34 (95% CI 0.18-0.67), reported… 421 more words


What’s New in Limb Lengthening/Deformity Correction: Level I and II Studies

Every month, JBJS publishes a Specialty Update—a review of the most pertinent and impactful studies published in the orthopaedic literature during the previous year in 13 subspecialties. 658 more words

What's New

Did reports of side effects contribute to drop in bone drug use?

The Journal of Bone and Mineral Research recently published a study that examines effects of media reports on the use of oral bisphosphonates. Google trends were utilized to get data from 1996 to 2012 for the media reports; the Medical Expenditure Panel Survey and the National Inpatient Sample were used to obtain data regarding fracture outcomes in the United States. 194 more words