Tags » Bisphosphonates

Osteoporosis Drugs Not Effective as Claimed

Drugs being prescribed for osteoporosis, bisphosphonates, are not worth the cost and risk of side effects, according to a paper published in the British Medical Journal which analyzed data from 33 previous studies. 214 more words

Injury Treatment

Bisphosphonates for the prevention and treatment of osteoporosis

Osteoporosis is a systemic skeletal disorder characterized by bone loss, which leads to impaired bone strength and an increased risk of fractures. Two million fractures are attributed to osteoporosis annually in the United States and they are associated with serious morbidity and mortality. 124 more words

03 (October 2015)

Bisphosphonates Curb Bones Breaks in Women With T2D

Bisphosphonate therapy was effective for reducing fracture incidence among postmenopausal women with diabetes, a post hoc analysis of randomized trial data found.

Among women with diabetes, the relative risk of nonvertebral fracture was 0.52 (95% CI 0.33-0.80) and the relative risk of morphometric vertebral fracture was 0.34 (95% CI 0.18-0.67), reported… 421 more words


What’s New in Limb Lengthening/Deformity Correction: Level I and II Studies

Every month, JBJS publishes a Specialty Update—a review of the most pertinent and impactful studies published in the orthopaedic literature during the previous year in 13 subspecialties. 658 more words

What's New

Did reports of side effects contribute to drop in bone drug use?

The Journal of Bone and Mineral Research recently published a study that examines effects of media reports on the use of oral bisphosphonates. Google trends were utilized to get data from 1996 to 2012 for the media reports; the Medical Expenditure Panel Survey and the National Inpatient Sample were used to obtain data regarding fracture outcomes in the United States. 194 more words


Alendronate prevents early joint degeneration following ACL injury

Our recent paper, Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice, published in Arthritis Research & Therapy, investigates the effect of a current osteoporosis treatment, alendronate, on joint health following injury. 130 more words

Acl Rupture

Study: 2 Generic Drugs May Reduce Breast Cancer Deaths

ATLANTA (CBS Atlanta) — Two inexpensive generic drugs could held reduce breast cancer deaths in women who develop the disease after menopause, according to new research. 517 more words