Tags » Bisphosphonates

Did reports of side effects contribute to drop in bone drug use?

The Journal of Bone and Mineral Research recently published a study that examines effects of media reports on the use of oral bisphosphonates. Google trends were utilized to get data from 1996 to 2012 for the media reports; the Medical Expenditure Panel Survey and the National Inpatient Sample were used to obtain data regarding fracture outcomes in the United States. 194 more words


Alendronate prevents early joint degeneration following ACL injury

Our recent paper, Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice, published in Arthritis Research & Therapy, investigates the effect of a current osteoporosis treatment, alendronate, on joint health following injury. 130 more words

Acl Rupture

Study: 2 Generic Drugs May Reduce Breast Cancer Deaths

ATLANTA (CBS Atlanta) — Two inexpensive generic drugs could held reduce breast cancer deaths in women who develop the disease after menopause, according to new research. 517 more words


Thousands of breast cancer deaths could be prevented by drug that prevent bone thinning

  • 50,000 new cases of breast cancer are diagnosed by doctors each year
  • Scientists find bone thinning drugs could prevent 1,300 deaths a year
  • The 5p pill slashes risk of cancer spreading to bone by 28 per cent…
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Name: Clodronate, Denusumab, Zometa, Aredia

Dosage: use as directed


Side Effects: sometimes osteonecrosis of the jaw


A German study in 1998 showed clodronate reduced metastases by 50% (in the bone only, I believe) and a… 455 more words

Filling the stone holes: my osteoporosis journey (so far)

A while back I learned I have osteoporosis.

This suuuuuuucks.

It’s not entirely unexpected — years of prednisone, weeks at a time of being ill in bed, an inability to exercise regularly and a strong genetic predisposition converged to make this more a slap I saw coming than a sucker punch. 1,165 more words


JBJS Reviews Editor’s Choice–Bisphosphonate-Related Femoral Fractures

In December 1996, a group of investigators reported the results of the Fracture Intervention Trial, a randomized controlled trial that compared the effect of alendronate plus calcium or calcium supplementation alone on the risk of fractures in women who already had evidence of vertebral fractures. 806 more words

Editor's Choice