Tags » Cushing's Syndrome
Hypercortisolemia in Cushing’s syndrome can be controlled with Metopirone therapy, according to recent study findings published in The Journal of Clinical Endocrinology & Metabolism.
John Newell-Price, PhD, FRCP, of the University of Sheffield in the United Kingdom, and colleagues evaluated 195 patients with Cushing’s syndrome to determine the effect of Metopirone (metyrapone, HRA Pharma) on the control of excess cortisol. 364 more words
Measuring 24-hour urinary free cortisol with liquid chromatography-mass spectrometry is the most accurate first-line diagnostic tool for diagnosing Cushing’s syndrome in adults, according to research published in The Journal of Clinical Endocrinology & Metabolism. 419 more words
The authors report the case of a 56-year-old woman who was diagnosed with Cushing’s disease 6 years earlier. At the moment of diagnosis, she presented a clinical picture of serious hypercortisolism with dramatic signs and symptoms including fatigue, weight loss, visceral obesity (BMI-29.5 kg/m2), “buffalo hump,” “moon face,” plethora, thin skin, hirsutism, hemorrhagic diathesis, purplish skin striae, proximal limbs muscle atrophy, and weakness as well as severe hypokalemia, hypertension, and secondary diabetes with high (about 70 U/day) insulin demand. 1,582 more words
A 49-year-old Caucasian female with no significant medical history was referred for evaluation of primary hyperparathyroidism. She reported increased thirst and urination and weight gain of 10 lbs in the previous year. 1,327 more words