Tags » Cushing's Syndrome

Urinary free cortisol measurement most accurate first-line test for Cushing's syndrome diagnosis

Ceccato F, et al. J Clin Endocrinol Metab. 2015;doi:10.1210/jc.2015-2507.

Measuring 24-hour urinary free cortisol with liquid chromatography-mass spectrometry is the most accurate first-line diagnostic tool for diagnosing Cushing’s syndrome in adults, according to research published in The Journal of Clinical Endocrinology & Metabolism. 419 more words

Cushing's

CASE 8- A CASE OF CUSHING'S DISEASE

Original case by Kurowska et al

The authors report the case of a 56-year-old woman who was diagnosed with Cushing’s disease 6 years earlier. At the moment of diagnosis, she presented a clinical picture of serious hypercortisolism with dramatic signs and symptoms including fatigue, weight loss, visceral obesity (BMI-29.5 kg/m2), “buffalo hump,” “moon face,” plethora, thin skin, hirsutism, hemorrhagic diathesis, purplish skin striae, proximal limbs muscle atrophy, and weakness as well as severe hypokalemia, hypertension, and secondary diabetes with high (about 70 U/day) insulin demand. 1,582 more words

CASE 5- A CASE OF HYPERCALCEMIA

Original Case by Kuhadiya et al (AACE Case reports)

A 49-year-old Caucasian female with no significant medical history was referred for evaluation of primary hyperparathyroidism. She reported increased thirst and urination and weight gain of 10 lbs in the previous year. 1,327 more words

Cortendo plans tax-fuelled shift to Dublin

Cortendo, a Swedish-American biopharmaceutical company that has invested millions developing treatments for rare conditions such as Cushing’s syndrome, is the latest global drug company to propose a move to Ireland for tax reasons. 305 more words

Cushing's

CASE 2 - AN INTERESTING CASE OF PITUITARY MACROADENOMA

ORIGINAL CASE Johnston et al 

HISTORY
A 54-year-old woman was noted on a routine visit to her ophthalmologist to have bi-temporal hemianopia. She had reported difficulty with reading, but had not noted peripheral vision loss. 1,336 more words

Effects of Cushing’s syndrome on the human brain

Cushing’s syndrome (CS) is characterized by excessive exposure to cortisol, and is associated with both metabolic and behavioural abnormalities even after biochemical cure. Andela et al… 147 more words

Cushing's

Experts recommend tumor removal as first-line treatment for Cushing's syndrome

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for treating Cushing’s syndrome, a condition caused by overexposure to the hormone cortisol. 840 more words

Cushing's