Tags » Endocrinology

Clinical Thyroidology for the Public – Highlighted Article

From Clinical Thyroidology for the Public: While it is clear that overt hypothyroidism in the mother during pregnancy can affect the baby’s brain development or cause other problems with the pregnancy, it is not clear if subclinical hypothyroidism would have similar adverse effects. 47 more words

Medicine By Alexandros G. Sfakianakis

Could vitamin A deficiency result in diabetes?

Diabetes has become a pandemic, with hundreds of new cases being diagnosed daily. Diabetes is caused by the lack of insulin produced by beta cells (type 2 diabetes) or total absence of insulin (type 1 diabetes). 511 more words


Clinical and Genetic Features of 64 Young Male Paediatric Patients with Congenital Hypogonadotropic Hypogonadism (CHH)



The diagnosis of congenital hypogonadotropic hypogonadism (CHH) in prepuberty has always been challenging. Here, we aimed at studying the clinical and genetic features of paediatric CHH, especially the phenotype of hypospadias and dual defects (patients showing hypothalamic and/or pituitary defects and testicular hypoplasia), so as to have a better understanding of CHH. 268 more words

Medicine By Alexandros G. Sfakianakis

Neural androgen receptor overexpression affects cell number in the spinal nucleus of the bulbocavernosus


The spinal nucleus of the bulbocavernosus (SNB) is a sexually dimorphic neuromuscular system in which masculinization of cell number is thought to depend on perinatal androgen action in non-neural targets, but masculinization of cell size is thought to depend primarily on adult androgen action on SNB cells themselves. 145 more words

Medicine By Alexandros G. Sfakianakis

Epigenetic dysregulation in adrenocortical carcinoma, a systematic review of the literature

Publication date: Available online 19 August 2017
Source:Molecular and Cellular Endocrinology
Author(s): P.K.C. Jonker, V.M. Meyer, S. Kruijff
Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with a poor prognosis. 112 more words

Medicine By Alexandros G. Sfakianakis