Tags » Experimental Design

How many observations do I need?

When planning your study, the sample size seems to be one of the most important questions. Each additional observation will cost money, time, and causes additional work. 856 more words

Experimental Design

Where to Start.

In the up-coming posts we will, for example, cover such topics as the choice of statistical software, what to do if the groups in ANOVA are not of equal size, how to interpret the results of a logistic regression model and what to keep in mind when planning a questionnaire. 482 more words

Experimental Design

Direct Microinjection of SmartFlares

We’ve so far, not seen any response of the VEGF SmartFlares to treatment of our cells with DMOG. Combined with the punctate distribution of the signal, we have no evidence that the SmartFlares make it to the cytosol in 18 hours. 541 more words

Project: Nanoflares

Source of chloroquine-induced vacuoles

In a recent post, I was musing about why the SmartFlares weren’t in the swollen chloroquine-induced vacuoles. Out of interest more than anything, I did a quick experiment to see what would happen if I pre-labelled the endocytic pathway with one coloured dextran, then added in a second with the chloroquine. 276 more words

Project: Nanoflares

Place matters for poverty

One of the concerns that emerged from the recent scandal about apparently fictitious data in a published poll about support for same-sex marriage was whether public pollsters are less transparent in their methods than social scientists.  93 more words

Quantitative Data Analysis

Do social scientists do better than pollsters?

One of the concerns that emerged from the recent scandal about apparently fictitious data in a published poll about support for same-sex marriage was whether public pollsters are less transparent in their methods than social scientists.  93 more words

Chapter 3