High prevalence and functional effects of serum antineuronal antibodies in patients with gastrointestinal disorders

Abstract

Background

Antineuronal antibodies can be associated with both gastrointestinal (GI) and brain disorders. For example, antibodies against the potassium channel subunit dipeptidyl-peptidase-like protein-6 (DPPX) bind to neurons in the central nervous system (CNS) and myenteric plexus and cause encephalitis, commonly preceded by severe unspecific GI symptoms. 242 more words

Medicine By Alexandros G. Sfakianakis

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00302841026182