Everyone loves a cocktail, right? I know I do. Here’s what goes into my favourite cocktail of the moment. Prednisolone, Levetiracetam, Azathioprine, AdCal D3, Omeprazole and Venlafaxine XL. 521 more words
Tags » NMDA
Tocilizumab in autoimmune encephalitis refractory to rituximab: an institutional cohort study
Lee WJ, Lee ST, Moon J, et al.
Neurotherapeutics 2016; 13:824-832.
A considerable portion of autoimmune encephalitis (AE) does not respond to conventional immunotherapies and subsequently has poor outcomes. 254 more words
Paraneoplastic and Autoimmune Encephalitis refers to a heterogeneous group of neurologic conditions whereby autoantibody formation disrupts normal neuronal and neurologic function. Because of their relatively recent discovery (basically last 20 years), more and more cases are being recognized in the clinical setting, and more and more patients are being suspected of having “autoimmune encephalitis.” However, I would caution any provider against considering autoimmune or paraneoplastic encephalitis in the differential diagnosis of a patient with unexplained altered mental status. 538 more words
MOA: multiple including blockade of nmda and Calcium channels
Magnesium has multiple advantages including:
- Reduced opioid reqs post op
- Reduced Mac with tiva… 106 more words
Reversal of evoked gamma oscillation deficits is predictive of antipsychotic activity with a unique profile for clozapine. (2016)
Recent heuristic models of schizophrenia propose that abnormalities in the gamma frequency cerebral oscillations may be closely tied to the pathophysiology of the disorder, with hypofunction of N-methyl-d-aspartate receptors (NMDAr) implicated as having a crucial role. 248 more words