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Seeking to expand CAR-T's reach, Novartis snags new regulatory milestones for Kymriah

Even as Celgene reportedly considers buying CAR-T player Juno Therapeutics, Novartis has its own plans to keep a leadership position in the field. On Wednesday, the drugmaker announced that Kymriah won regulatory milestones on both sides of the Atlantic as it seeks to grow its prospects with the cutting-edge technology. 116 more words

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Why didn't the anti-CD19 CAR-T immunotherapies from Novartis or Kite suffer from neurotoxicity adverse events as the ones from Juno did?

Brief Background on Anti-CD19 CAR-T Immunotherapy

So far, CAR-T immunotherapy has been most successful against CD19-positive tumors such as Acute lymphoblastic leukemia – Wikipedia (specifically B-ALL). 1,386 more words

Cancer

POSITRACTION: More tools to save lives

2017-Dec-31

https://www.popsci.com/best-science-stories-2017#page-3

SCIENCE
The most uplifting science stories of 2017
A few bright points throughout the year.
By Rachel Feltman  4 hours ago

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Positraction

California Supreme Court Exposes Drug Makers to Additional Liability

SAN FRANCISCO (AP) — A sharply divided California Supreme Court ruled Thursday that pharmaceutical companies can be held liable for warning labels on generic versions of drugs they once made even after they’ve sold the drugs to other companies and stopped manufacturing them. 517 more words

News

The First FDA-Approved Gene Therapy Can Cure a Type of Blindness—But May Cost $1 Million

The Food and Drug Administration (FDA) on Tuesday approved the first true gene therapy in the U.S.—Luxturna from Spark Therapeutics, which treats a form of inherited vision loss which can lead to blindness. 334 more words

Health

The High Cost of Living

By THÉRÈSE MARGOLIS    

In August, the U.S. Food and Drug Administration (FDA) approved the first-ever gene-altering treatment for a rare form of childhood leukemia.

This milestone medical breakthrough allows scientists to genetically modify a patient’s own cells to fight cancer, turning them into a “living drug.” 581 more words

Www.pulsenewsmexico.com

New Migraine Drugs May Help Prevent Headaches Before They Start

One in seven Americans suffers from migraines, and medications currently prescribed to prevent them—like blood-pressure drugs and antidepressants—don’t work for many people. But two new studies offer hope for those who haven’t respond well to existing treatments. 831 more words