Tags » Pharmacology

What happens to Theophylline in the body (Pharmacology)?

Absorption:

  • Variable

Distribution:

  • Variable

Metabolism:

  • Liver
  • Metabolized by CYP1A2 and CYP3A4

Elimination:

  • Urine
  • Half life (Non-smoker): 8hr
  • Half life (Smoker): 4-5hr
  • Clearance: 1.45ml/min/kg
Aminophylline

Managing Sexual Assualt in Primary Care

Thanks to those who participated in a great discussion in AMR last week. I wanted to share some of what we talked about here…

Sexual assault is an unusal complaint inside of a primary care clinic.   652 more words

Management

[ARTICLE] Pharmacotherapy of Traumatic Brain Injury: State of the Science and the Road Forward: Report of the Department of Defense Neurotrauma Pharmacology Workgroup - Full Text HTML

Abstract

Despite substantial investments by government, philanthropic, and commercial sources over the past several decades, traumatic brain injury (TBI) remains an unmet medical need and a major source of disability and mortality in both developed and developing societies. 226 more words

Traumatic Brain Injury

Faster and Safer Treatments for Depression

I previously wrote about Selective Serotonin Reuptake Inhibitors (SSRIs), the most commonly prescribed antidepressants. In this post, I want to discuss a novel class of compounds that may be able to treat depression faster and with fewer side effects. 877 more words

Microfluid device can control neurons and delivery drugs wirelessly.

A team of researchers from Washington University, National Institutes of Health and University of Illinois have developed a wireless device the width of a human hair that can be implanted in the brain and activated by remote control to deliver drugs.  704 more words

Healthinnovations

What happens to Ciprofloxacin in the body (Pharmacology)?

Absorption:

  • About 50 – 85% of the drug is absorbed when taken orally.

Distribution:

  • Distributed widely around the body.
  • Cerebrospinal fluid distribution is minimal (10%) but increases with inflammation of the meninges (14 – 37%).
  • 20 more words
Ciprofloxacin