Tags » Platinum Drugs

Platinum Resistance is in the Eye of the Beholder

I was recently apprised of an online conversation surrounding the treatment of platinum refractory and platinum resistant ovarian cancer. To clarify our terminology, platinum refractory disease refers to cancer that progresses during platinum therapy. 660 more words


A Gene Test to Identify Chemo-Resistant Ovarian Cancers

Ovarian cancer causes more deaths than any other reproductive cancer, largely because there is little doctors can do to prolong women’s lives after they are diagnosed. 724 more words


The Role of the Platinum Derivatives in Cancer Therapy

The discovery of cisplatinum and the subsequent development of its derivatives (carboplatin and oxaliplatin) represent an interesting saga in modern oncology. When Rosenberg observed in 1960s that platinum electrodes in salt water baths inhibited the growth of bacteria and fungi it lead to the isolation of cis-dichloro diamine platinum (cisplatin). 309 more words

Cancer Drug Development