Tags » Pre-print

Pre-print: Substrate conformational dynamics drive structure-specific recognition of gapped DNA by DNA polymerase

T.D. Craggs, M. Sustarsic, A. Plochowietz, M. Mosayebi, H. Kaju, A. Cuthbert, J. Hohlbein, L. Domicevica, P.C. Biggin, J.P. K. Doye, A.N. Kapanidis, bioRxiv, 2018 [ 232 more words

Open Access

Pre-print: Precision and accuracy of single-molecule FRET measurements - a worldwide benchmark study

B. Hellenkamp, S. Schmid, O. Doroshenko, O. Opanasyuk, R. K├╝hnemuth, S. Rezaei Adariani, A. Barth, V. Birkedal, M.E. Bowen, H. Chen, T. Cordes, T. Eilert, C. 253 more words

Open Access

Pre-print: Simple nanofluidic devices for high-throughput, non-equilibrium studies at the single-molecule level

C. Fijen, M. Fontana, S.G. Lemay, K. Mathwig, J. Hohlbein, bioRxiv, 2017, [link]

Single-molecule detection schemes offer powerful means to overcome static and dynamic heterogeneity inherent to complex samples. 161 more words

Open Access

CRISPR Digest #14

Two years ago, in spring 2015, Liang et al. published the first report of gene-editing in human embryos using CRISPR/Cas9 (mentioned previously┬áhere, … 1,096 more words

Factual