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Presentation: Evidence for rivaroxaban in combination with ritonavir: should we CYPmly avoid concomitant use?
Durning my internal medicine rotation at St. Paul’s I did a patient case presentation on the combination of rivaroxaban and ritonavir (a known CYP3A4 inhibitor). In this particular scenario, the patient was non-adherent to dabigatran and required a once daily dosing option for an anticoagulant in the treatment of PE. 67 more words
Last week, I delivered an overview of the available literature on trimethoprim/sulfamethoxazole (Septra) dosing in MRSA infections to the pharmacists at Burnaby Hospital. Overall, there is little direct evidence to suggest a benefit of one dose over another for infections. 82 more words