Tags » Tace

An unsilent woman

Tace was almost unknown as a given name in London before the Quaker printer Andrew Sowle and his wife named their fourth daughter in 1666. It was a little less rare elsewhere; it crops up from the 1540s in the earliest Church of England registers, notably in Gloucestershire and the west. 602 more words

17th Century

EnSens, or how to overcome FRET assay limitations

How can you overcome the limits of FRET based protease activity assays for MMPs, ADAMs, Thrombin, Furin and Factor Xa?

Usually screenings for inhibitors of diverse protease activities are conducted with FRET or FRET-like assays, in which the protease substrate has to be coupled to a fluorophore and a quencher. 525 more words

Drug Discovery