Tags » Virology

Nanoparticle vaccines against dengue fever?

Every year more than 350 million people in over 120 countries contact dengue fever, which can cause symptoms ranging from aching muscles and a skin rash to life-threatening haemorrhagic fever. 502 more words


How is the hepatitis C-like hepacivirus of horses transmitted?

In 2011, a new virus was identified in dogs that were suffering from respiratory disease. Analysis revealed that this virus – at the time named canine hepacivirus (CHV) – was the closest known relative of the human virus hepatitis C (HCV), which infects millions of people across the world and can cause serious liver problems. 592 more words


Zoonotic Hepatitis E Virus

During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of indigenous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. 54 more words


Herpesviruses as Pioneers in Cell Biology

Intracytoplasmic vesicular transport is well established; nucleo-cytoplasmic transport has so far been thought to be restricted to passage through the nuclear pore either passively, if size permits, or via karyopherin-mediated active transport. 330 more words


A new era of norovirus research begins after successfully growing the virus in the lab

Human noroviruses – the leading viral cause of acute diarrhea around the world – have been difficult to study because scientists had not found a way to grow them in the lab. 1,216 more words


Closing in on the causes of host shutoff

When a virus enters a cell it relies on the molecular machinery of its host to help it replicate. In particular, the virus relies on the ribosomes in the host cell to translate viral messenger RNA (mRNA) into polypeptides. 403 more words


Latency in Herpes Simplex Virus 1

Herpes simplex virus 1 (HSV-1) is a neurotropic virus that establishes a life-long latent infection in the trigeminal ganglia (TG) of the infected human host. From time to time the virus asymptomatically or symptomatically reactivates from the latency stage producing epithelial lesions, most of the time on the face but also in the eye, inducing severe pathologies such as keratitis. 852 more words